Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street Children’s Hospital NHS Foundation Trust, University of Leicester - College of Life Sciences, Great Ormond Street Children’s Hospital NHS Foundation Trust, Great Ormond Street Children’s Hospital NHS Foundation Trust, Great Ormond Street Children’s Hospital NHS Foundation Trust, Great Ormond Street Children’s Hospital NHS Foundation Trust, University of Leicester, University of Leicester - College of Life Sciences, Government of the United Kingdom - Biomedical Research Centre, Great Ormond Street Children’s Hospital NHS Foundation Trust, Great Ormond Street Children’s Hospital NHS Foundation Trust and University of Leicester - College of Life Sciences