Wayne State University, affiliation not provided to SSRN, affiliation not provided to SSRN, Vancouver General Hospital, affiliation not provided to SSRN, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS) - Ospedale Sacro Cuore Don Calabria, affiliation not provided to SSRN, Instituto Mexicano del Seguro Social (IMSS) - Instituto Mexicano del Seguro Social, Harvard University - Massachusetts General Hospital, Universidad de Barcelona - Hospital Clínic Barcelona, affiliation not provided to SSRN, affiliation not provided to SSRN, Universitat de Barcelona - IDIBELL, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Harvard University - Brigham and Women's Hospital, Istanbul Medeniyet University - Department of Pathology, affiliation not provided to SSRN, affiliation not provided to SSRN, Medical University of Graz, Universidad de Barcelona - Hospital Clínic Barcelona, affiliation not provided to SSRN, Wayne State University - School of Medicine, Wayne State University, affiliation not provided to SSRN, University of Gothenburg, University of Chicago, Harvard University - Massachusetts General Hospital, Universitätsklinikum Leipzig, Belfast Health and Social Care Trust, affiliation not provided to SSRN and University of Michigan at Ann Arbor