Tel Aviv University - Rabin Medical Center, Tel Aviv University - Rabin Medical Center, Charité - Universitätsmedizin Berlin, Hospital JM Ramos, Koc University, Hospital Universitario San Ignacio, Charité - Universitätsmedizin Berlin, Tel Aviv University, Hospital Universitari Vall d'Hebron of Barcelona, Hebrew University of Jerusalem - Hadassah Medical Center, University of Verona, Universitat de Barcelona, Koc University, University of Verona, The University of Sydney, Mayo Clinic - Department of Ophthalmology, Charité - Universitätsmedizin Berlin, Hospital JM Ramos, Tel Aviv University - Rabin Medical Center, Hospital Aleman, Children’s Hospital at Westmead, University of Barcelona - Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hebrew University of Jerusalem - Hadassah Medical Center, Tel Aviv University - Rabin Medical Center, Mayo Clinic - Department of Neurology and Laboratory Medicine and Pathology and the Center for MS and Autoimmune Neurology, Clinica Alemana de Santiago SA, Tel Aviv University - Rabin Medical Center, IRCCS Mondino Foundation Pavia, Ludwig Maximilians University LMU University Hospital Munich, IRCCS Mondino Foundation Pavia, Charité - Universitätsmedizin Berlin, LMU University Hospital, University Medical Center Hamburg- Eppendorf, Tel Aviv University - Rabin Medical Center, Charité Universitätsmedizin Berlin - Institute of Biometry and Clinical Epidemiology, University of Oxford, Charité - Universitätsmedizin Berlin, Hebrew University of Jerusalem - Hadassah Medical Center, Harvard University - Massachusetts General Hospital, Hospital Aleman, Tel Aviv University - Rabin Medical Center, Hospital JM Ramos, University of Verona - University of Verona, Charité - Universitätsmedizin Berlin, University of Botswana, Hospital JM Ramos, Charité - Universitätsmedizin Berlin, University of Oxford, Nitte University, Government of the United Kingdom - Moorfields Eye HospitalNHS Foundation Trust - NIHR Biomedical Research Centre, Mayo Clinic - Department of Neurology and Laboratory Medicine and Pathology and the Center for MS and Autoimmune Neurology, Translational Neuroimmunology Group, The University of Sydney, Mahidol University, Charité - Universitätsmedizin Berlin, Hospital Universitari Vall d'Hebron of Barcelona, Hospital Universitari Vall d'Hebron of Barcelona - Department of Neurology-Neuroimmunology, Hospital JM Ramos, Tianjin Medical University - Department of Neurology, University of Botswana, Tel Aviv University - Rabin Medical Center, Mahidol University, Charité - Universitätsmedizin Berlin, Mayo Clinic, Pontificia Universidad Javeriana, Pontificia Universidad Javeriana, University of Florida, Hospital Universitari Vall d'Hebron of Barcelona - Department of Neurology-Neuroimmunology, Charité - Universitätsmedizin Berlin, Tianjin University, Nanyang Technological University (NTU), Hebrew University of Jerusalem, Pontificia Universidad Javeriana, LMU University Hospital, Tan Tock Seng Hospital, Charité - Universitätsmedizin Berlin, University of Colorado, Aurora - Anschutz Medical Campus, Charité Universitätsmedizin Berlin - Experimental and Clinical Research Center and NeuroCure Clinical Research Center, Charité - Universitätsmedizin Berlin and Charité - Universitätsmedizin Berlin