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Anne Bigot

Sorbonne University

SCHOLARLY PAPERS

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Scholarly Papers (1)

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Shuffling of HVRs in AAV Capsid Reveals a Context-Dependent Role for HVR5 in Peripheral Tissue Detargeting While Ensuring CNS Targeting

Number of pages: 55 Posted: 12 Nov 2025
Christian Leborgne, Novella Tedesco, Bérangère Bertin, Sophie Frin, Justine Nozi, Ante Mihaljevic, Valle Montalvo-Romeral, Stephanie Astord, Anne Bigot, Nathalie Daniele, Laetitia Van Wittenberghe, Laura Cancedda, Andrea Contestabile, Maria Grazia Biferi, Piera Smeriglio, Tiziana La Bella, Giuseppe Ronzitti and Sneak Peek Administrator
Genethon, Genethon, Genethon, Genethon, Genethon, Genethon, Genethon, Sorbonne University, Sorbonne University, Genethon, Genethon, Istituto Italiano di Tecnologia, Istituto Italiano di Tecnologia, Sorbonne University, Sorbonne University, Genethon, Genethon and Independent
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Adeno-associated virus, AAV gene therapy, Capsid engineering, CNS targeting, AAV variants, Vector specificity, Neurological disorders