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Jiahui Hou

University of Pittsburgh

200 Lothrop Street

Pittsburgh, PA 15232

  • University of Pittsburgh

SCHOLARLY PAPERS

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Scholarly Papers (1)

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Brain-Regional Gene Expression Imputed from the Blood Transcriptome by BrainGENIE Recapitulates Dysregulation Observed in the Postmortem Brain in Alzheimer’s Disease

Number of pages: 39 Posted: 16 Nov 2025
Stephen J. Glatt, Jiahui Hou, Ali Razavi, Shu-Ju Lin, Chunling Zhang, William S. Kremen, Christine Fennema-Notestine, Jeremy A. Elman, Peter Holmans, Stephen V. Faraone, Chris Gaiteri and Jonathan L. Hess
affiliation not provided to SSRN, University of Pittsburgh, affiliation not provided to SSRN, Cedars-Sinai Medical Center, affiliation not provided to SSRN, University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of California, San Diego (UCSD), Cardiff University, State University of New York (SUNY) - Department of Psychiatry, affiliation not provided to SSRN and affiliation not provided to SSRN
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Abstract:

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Gene Imputation, Transcriptome Imputation, Alzheimer's disease, Brain Gene Expression, TWAS, Blood-based biomarkers, Neurodegenerationdiscovery and prospective AD studies.