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Ivana Petrović Koshmak

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A Two-Dimensional Hyphenated Ion-Exchange Chromatography Platform for Simultaneous Assessment of AAV8 Capsid Ratios and Impurities in Upstream Processes

Number of pages: 40 Posted: 17 Dec 2025
Timotej Žvanut, Tjaša Kašček, Lara Vogrinčič, Petra Dekleva, Sandra Potušek, Anže Martinčič Celjar, Ivana Petrović Koshmak, Blaž Goričar, Mitja Martelanc, Aleš Štrancar and Andreja Gramc Livk
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Nova Gorica, affiliation not provided to SSRN and affiliation not provided to SSRN
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Abstract:

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Complex samples, upstream process (USP) monitoring, two-dimensional (2D) hyphenated liquid chromatography (LC), adeno-associated virus 8 (AAV8) analysis, partially filled capsids, full (F) capsid content.