Humanitas University, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Pisa, Università Vita-Salute San Raffaele - IRCCS San Raffaele Scientific Institute, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS) - Medical Oncology 1, affiliation not provided to SSRN, IRCCS Humanitas Research Hospital, Fondazione IRCCS Istituto Nazionale dei Tumori, affiliation not provided to SSRN, University of Pisa, Università Vita-Salute San Raffaele - San Raffaele Hospital, affiliation not provided to SSRN, Istituto Clinico Humanitas, Fondazione IRCCS Istituto Nazionale dei Tumori, affiliation not provided to SSRN, Fondazione Policlinico Universitario A. Gemelli IRCCS - Oncologia Medica, Careggi University Hospital of Florence - Clinical Oncology Unit, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS) - IRCCS Veneto Institute of Oncology (IOV-IRCCS), IRCCS Humanitas Research Hospital, Università Vita-Salute San Raffaele - IRCCS Ospedale San Raffaele, University of Pisa and affiliation not provided to SSRN