University of Catania, IRCCS Humanitas Research Hospital, affiliation not provided to SSRN, affiliation not provided to SSRN, Breast Center EUSOMA, University of Perugia, NHS Foundation Trust - Royal Marsden Hospital, University of Nottingham - Royal Derby Hospital, European Institute of Oncology (IEO) IRCCS - Division of New Drugs and Early Drug Development for Innovative Therapies, University of Oslo - Akershus University Hospital, University of Navarra - Clínica Universidad de Navarra, affiliation not provided to SSRN, IRCCS Policlinico San Donato, Medical University of Gdańsk, University of Antwerp and affiliation not provided to SSRN