Economic Evaluation of HIV Treatments: The I.CO.N.A. Cohort Study

Health Policy, Vol. 74, No. 3, pp. 304-313, November 2005

Posted: 21 Nov 2007 Last revised: 24 Dec 2007

See all articles by Monica Merito

Monica Merito

Scuola Superiore Sant'Anna di Pisa - Laboratory of Economics and Management (LEM)

Andrea Bonaccorsi

Scuola Superiore Sant'Anna di Pisa - Laboratory of Economics and Management (LEM)

Fabio Pammolli

Polytechnic University of Milan - Department of Management, Economics and Industrial Engineering; CERM Foundation

Massimo Riccaboni

KU Leuven - Department of Managerial Economics, Strategy, and Innovation; IMT Institute for Advanced Studies

Gianluca Baio

University College London

Claudio Arici

Ospedali Riuniti di Bergamo

Antonella D'Arminio Monforte

University of Milan - Dipartimento di Medicina, Chirurgia ed Odontoiatria

Patrizio Pezzotti

Istituto Superiore di Sanità

Dario Corsini

Informa

Roberto Cauda

Catholic University of the Sacred Heart of Milan

Vincenzo Colangeli

University of Bologna

Giuseppe Pastore

Università degli Studi di Bari “Aldo Moro” (UNIBA) - Faculty of Medicine and Surgery

Abstract

Objective: To describe the changes in costs of care for HIV - positive patients in Italy after the spread of antiretroviral combination therapies (HAART).

Methods: Five thousand four hundred and twenty - two patients from the I.CO.N.A. (Italian Cohort Naive Antiretrovirals) study were followed between 1997 and 2002. Costs included antiretroviral therapies (ART), hospital admissions, prophylaxis, and main laboratory examinations. The perspective was that of the National Health Service.

Results: Admission costs per person - year decreased from 2148 euro in 1997 to 256 in 2002, while the average annual costs of ART increased from 2145 to 3149 euro (1997 prices). From 1997 to1999, ART costs increased from 42.3 to 85.9f the total, while admission costs decreased from 42.3 to 7.0 nd prophylaxis from 7.3 to 1.7àThe breakdown of ART costs shows how dual therapies decreased over time in favor of HAART, falling from 26.8n 1997 to 5.9n 2002. Patients with fewer than five treatment switches had the lowest costs distributions over the entire observation period.

Conclusions: From 1997 to 2002 inpatient costs progressively decreased in favor of antiretroviral therapy. Annual average costs per patient decreased, while total direct costs increased over time: health resources, initially concentrated on hospitalized patients were then distributed over a growing number of subjects.

Keywords: HIV infection, HAART, Health resources, Costs per person-year

Suggested Citation

Merito, Monica and Bonaccorsi, Andrea and Pammolli, Fabio and Riccaboni, Massimo and Baio, Gianluca and Arici, Claudio and D'Arminio Monforte, Antonella and Pezzotti, Patrizio and Corsini, Dario and Cauda, Roberto and Colangeli, Vincenzo and Pastore, Giuseppe, Economic Evaluation of HIV Treatments: The I.CO.N.A. Cohort Study. Health Policy, Vol. 74, No. 3, pp. 304-313, November 2005, Available at SSRN: https://ssrn.com/abstract=1031638

Monica Merito

Scuola Superiore Sant'Anna di Pisa - Laboratory of Economics and Management (LEM) ( email )

Piazza Martiri della Liberta, 33
Pisa, I-56127
Italy

Andrea Bonaccorsi

Scuola Superiore Sant'Anna di Pisa - Laboratory of Economics and Management (LEM) ( email )

Piazza Martiri della Liberta, 33
Pisa, I-56127
Italy
+39 05 088 3323 (Phone)
+39 05 088 3344 (Fax)

Fabio Pammolli (Contact Author)

Polytechnic University of Milan - Department of Management, Economics and Industrial Engineering ( email )

Via Lambruschini 4C - building 26/A
Milano, 20156
Italy

CERM Foundation ( email )

Via Fiorentina, 1
Siena, Siena 53100
Italy

HOME PAGE: http://www.cermlab.it

Massimo Riccaboni

KU Leuven - Department of Managerial Economics, Strategy, and Innovation ( email )

Naamsestraat 69 bus 3500
Leuven, 3000
Belgium

IMT Institute for Advanced Studies ( email )

Complesso San Micheletto
Lucca, 55100
Italy

Gianluca Baio

University College London ( email )

Gower Street
London, WC1E 6BT
United Kingdom

Claudio Arici

Ospedali Riuniti di Bergamo ( email )

Largo Barozzi, 1
Bergamo, Bergamo 24128
Italy

Antonella D'Arminio Monforte

University of Milan - Dipartimento di Medicina, Chirurgia ed Odontoiatria ( email )

Via A. Di Rudinì, 8
Milano, 20142
Italy

Patrizio Pezzotti

Istituto Superiore di Sanità ( email )

Viale Regina Elena 299
Roma, 00161
Italy

Dario Corsini

Informa ( email )

Via dei Magazzini Centrali, 31
Roma, 00154
Italy

Roberto Cauda

Catholic University of the Sacred Heart of Milan ( email )

Roma
Italy

Vincenzo Colangeli

University of Bologna ( email )

Piazza Scaravilli 2
Bologna, 40100
Italy

Giuseppe Pastore

Università degli Studi di Bari “Aldo Moro” (UNIBA) - Faculty of Medicine and Surgery ( email )

Bari 70124
Italy

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