Space: Negative Selection, Physical Constraint, and Symmetry

13 Pages Posted: 13 Jun 2010  

Marvin Eli Kirsh

California State University, Los Angeles

Date Written: June 11, 2010


A descriptive role is suggested for uracil as a temporal divide in the immediate aspects of metabolism verses long term maintained genetic transmission. In particular, details of the mechanism of excision repair of uracil from DNA based on differential parameters of spatial distortion of the planar uracil molecule within the DNA helix verses RNA, when viewed in analogy to a proposed model for space involving the substitution of the act of mirroring for the element of time in processes and a descending complexity of structure with time of evolution, suggest the possibility that negative selection against decreased lifetime is the singular motive force of natural selection. The geometry of the Mobius strip, as it has a plane of mirroring symmetry, a twist able to account for torque in nature, an inversion of inside and out seen in biological structures, and an endless surface that can be accommodated to an atemporal account of physical processes is employed in a holistic model to elaborate a negative selection opposing death as zero volume or the logical existence of physical constraint to volumes that is represented as the ubiquitous inability of witnessing objects of any type to witness simultaneously both a self reflection and the reflection of self reflection. A role for uracil and its’ physical structure, in a model in which both are evolved from the mirroring of events of the witnessing of energies, is elaborated in which temporal aspects such as those entailed in existing models of natural evolution are considered inappropriate in perspectives that are oriented positively towards a successful comprehension of processes; focus is placed instead upon the geometry and arrangement of physical spaces.

Keywords: Cellular Energy Divide, Uracil, Mutation, Birth of Life

Suggested Citation

Kirsh, Marvin Eli, Space: Negative Selection, Physical Constraint, and Symmetry (June 11, 2010). Available at SSRN: or

Marvin Eli Kirsh (Contact Author)

California State University, Los Angeles ( email )

5151 State University Dr
Los Angeles, CA 90032
United States
323-263-0426 (Phone)


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