Molecular Aspects of Bacterial Resistance to Antibiotics

The International Conference Education and Creativity for a Knowledge Based Society – Medicine and Dental Medicine, 2012

Posted: 20 Mar 2013

Date Written: ` 2012

Abstract

Microbial resistance to antibiotics, a process known in the last two decades of rapid growth and uncontrolled worldwide, is widely accepted today as one of the major public health problems worldwide. It is manifested by severity of infections or extension of clinical symptoms, increasing systemic infections with high mortality, increased hospital stays and, not least, the costs imposed by them.

A key role in the emergence and development of bacterial resistance to antibiotics it is genetic variability. It is the result of one of the following events: genetic mutation or transfer of genetic material between organisms by transformation or conjugation, respectively tranducţie transposition. In this paper we present some of the mechanisms involved in genetically the emergence and development of bacterial resistance to antibiotics.

Suggested Citation

Bogdan-Ioan, Coculescu and Minerva, Ghinescu, Molecular Aspects of Bacterial Resistance to Antibiotics (` 2012). The International Conference Education and Creativity for a Knowledge Based Society – Medicine and Dental Medicine, 2012. Available at SSRN: https://ssrn.com/abstract=2235239

Ghinescu Minerva

Titu Maiorescu University ( email )

22, Dâmbovnicului Street, sector 4, 040051
Bucharest
Romania

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