Influence on Cardiomyocyte Oxidative Stress in Congestive Heart Failure Induced by Myocardial Ischemia Atheromatous
The International Conference Education and Creativity for a Knowledge Based Society – Medicine and Dental Medicine, 2012
Posted: 20 Mar 2013
Date Written: 2012
Based on data from the literature consulted on how oxidative stress is involved in the pathogenesis of congestive heart failure (CHF), this paper summarizes how myocardial contractile mass is reduced, the main pathogenic component shortages ASPIRO-repellent pump heart. Reduction of myocardial contractility under conditions of oxidative stress induced ischemic recognize a double mechanical process exacerbating cardiomyocyte premature death (necrosis and apoptosis) and qualitative alterations in cardiomyocyte organelles to survive oxidative stress existing functional myocardium and are overburdened. Of the two ways of affecting their numerical cardiomyocytes-induced apoptosis mechanism is introduced early and high rates.
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