Influence on Cardiomyocyte Oxidative Stress in Congestive Heart Failure Induced by Myocardial Ischemia Atheromatous

The International Conference Education and Creativity for a Knowledge Based Society – Medicine and Dental Medicine, 2012

Posted: 20 Mar 2013

See all articles by Ghinescu Minerva

Ghinescu Minerva

Titu Maiorescu University

V. Dincă

Independent

Hârşovescu Tudor

Independent

Manole Gheorghe

Titu Maiorescu University - School of Medicine and Pharmacy

Date Written: 2012

Abstract

Based on data from the literature consulted on how oxidative stress is involved in the pathogenesis of congestive heart failure (CHF), this paper summarizes how myocardial contractile mass is reduced, the main pathogenic component shortages ASPIRO-repellent pump heart. Reduction of myocardial contractility under conditions of oxidative stress induced ischemic recognize a double mechanical process exacerbating cardiomyocyte premature death (necrosis and apoptosis) and qualitative alterations in cardiomyocyte organelles to survive oxidative stress existing functional myocardium and are overburdened. Of the two ways of affecting their numerical cardiomyocytes-induced apoptosis mechanism is introduced early and high rates.

Suggested Citation

Minerva, Ghinescu and Dincă, V. and Tudor, Hârşovescu and Gheorghe, Manole, Influence on Cardiomyocyte Oxidative Stress in Congestive Heart Failure Induced by Myocardial Ischemia Atheromatous (2012). The International Conference Education and Creativity for a Knowledge Based Society – Medicine and Dental Medicine, 2012. Available at SSRN: https://ssrn.com/abstract=2235241

Ghinescu Minerva (Contact Author)

Titu Maiorescu University ( email )

22, Dâmbovnicului Street, sector 4, 040051
Bucharest
Romania

V. Dincă

Independent ( email )

Hârşovescu Tudor

Independent ( email )

Manole Gheorghe

Titu Maiorescu University - School of Medicine and Pharmacy ( email )

22, Dâmbovnicului Street, Sector 4, 040051
Bucharest
Romania

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