Does Consent Bias Research?
Am.J.Bioethics 13(4), 2013
11 Pages Posted: 6 Apr 2013
Date Written: April 4, 2013
Researchers increasingly rely on large data sets of health information, often linked with biological specimens. In recent years, the argument has been made that obtaining informed consent for conducting records-based research is unduly burdensome and results in “consent bias.” As a type of selection bias, consent bias is said to exist when the group giving researchers access to their data differs from the group denying access. Therefore, to promote socially beneficial research, it is argued that consent should be unnecessary. After analyzing the biostatistics evidence and bioethics arguments, the article concludes that (1) claims about the amount of consent bias are overstated; (2) commonly used statistical methods usually can account for consent bias; and (3) any residual effects of consent bias are below an acceptable level of imprecision and constitute a reasonable social cost for conducting ethically responsible research.
Keywords: research ethics, informed consent, consent bias, selection bias
JEL Classification: K31, K32
Suggested Citation: Suggested Citation