Methylparabens and Cosmetics: Toxicological Risk?

22 Pages Posted: 24 Aug 2013

Date Written: December 7, 2012

Abstract

The human population is exposed to man-made methylparabens (MP) from a variety of food and drink, cosmetics, and pharmaceutics industry sources. The cosmetic industry comprises the majority of MP exposures, which means that understanding dermal exposure is of utmost importance in order to characterize potential health risks. The purpose of this paper is to discuss the toxicokinetics of MP via dermal exposures. A hypothetical framework is proposed that illustrates toxicological mechanisms whereby MP may act as a tumor progressor as well as a tumor initiator. The margin of safety is also calculated to determine public health safety to current average dermal exposure to MP.

Keywords: methylparabens, parabens, cosmetics, cancer, tumor, initiator, progressor, margin of safety, public health

JEL Classification: I10, I18

Suggested Citation

Ciechanowski, Peter, Methylparabens and Cosmetics: Toxicological Risk? (December 7, 2012). Available at SSRN: https://ssrn.com/abstract=2314621 or http://dx.doi.org/10.2139/ssrn.2314621

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