Age-Related Changes in Object Processing and Contextual Binding Revealed Using fMR Adaptation

Journal of Cognitive Neuroscience 18:4, pp. 495–507, 2006

Fox School of Business Research Paper

13 Pages Posted: 14 May 2014

See all articles by Michael Chee

Michael Chee

Duke-NUS Graduate Medical School Singapore

Joshua Goh

National Institutes on Aging

Vinod Venkatraman

Temple University - Department of Marketing and Supply Chain Management; Temple University - Decision Neuroscience

Jiat Chow Tan

Independent

Angela Gutchess

University of Illinois at Urbana-Champaign - Department of Mathematics

Brad Sutton

University of Illinois at Urbana-Champaign - Department of Mathematics

Andy Hebrank

University of Illinois at Urbana-Champaign - Department of Mathematics

Eric Leshikar

University of Illinois at Urbana-Champaign - Department of Mathematics

Denise C. Park

University of Illinois at Urbana-Champaign - Department of Psychology

Date Written: 2006

Abstract

Using fMR adaptation, we studied the effects of aging on the neural processing of passively viewed naturalistic pictures composed of a prominent object against a background scene. Spatially distinct neural regions showing specific patterns of adaptation to objects, background scenes, and contextual integration (binding) were identified in young adults. Older adults did not show adaptation responses corresponding to binding in the medial-temporal areas. They also showed an adaptation deficit for objects whereby their lateral occipital complex (LOC) did not adapt to repeated objects in the context of a changing background. The LOC could be activated, however, when objects were presented without a background. Moreover, the adaptation deficit for objects viewed against backgrounds was reversed when elderly subjects were asked to attend to objects while viewing these complex pictures. These findings suggest that the elderly have difficulty with simultaneous processing of objects and backgrounds that, in turn, could contribute to deficient contextual binding.

Suggested Citation

Chee, Michael and Goh, Joshua and Venkatraman, Vinod and Chow Tan, Jiat and Gutchess, Angela and Sutton, Brad and Hebrank, Andy and Leshikar, Eric and Park, Denise C., Age-Related Changes in Object Processing and Contextual Binding Revealed Using fMR Adaptation (2006). Journal of Cognitive Neuroscience 18:4, pp. 495–507, 2006; Fox School of Business Research Paper. Available at SSRN: https://ssrn.com/abstract=2430353

Michael Chee

Duke-NUS Graduate Medical School Singapore ( email )

Singapore
Singapore

Joshua Goh

National Institutes on Aging ( email )

Bethesda, MD 20892
United States

Vinod Venkatraman (Contact Author)

Temple University - Department of Marketing and Supply Chain Management ( email )

Philadelphia, PA 19122
United States

Temple University - Decision Neuroscience ( email )

Philadelphia, PA 19122
United States

Jiat Chow Tan

Independent

No Address Available
United States

Angela Gutchess

University of Illinois at Urbana-Champaign - Department of Mathematics

Brad Sutton

University of Illinois at Urbana-Champaign - Department of Mathematics

Andy Hebrank

University of Illinois at Urbana-Champaign - Department of Mathematics

Eric Leshikar

University of Illinois at Urbana-Champaign - Department of Mathematics

Denise C. Park

University of Illinois at Urbana-Champaign - Department of Psychology ( email )

603 East Daniel
Champaign, IL 61820
United States

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