Unusual Side Effects of Interferon Beta-1a in Patient with Multiple Sclerosis

Mat Soc Med, 2012

3 Pages Posted: 11 Sep 2015

See all articles by Maryam Tavakoli

Maryam Tavakoli

Islamic Azad University (IAU)

Seyed-Mohammad-Yousof Mostafavi-Pour-Manshadi

Respiratory Epidemiology and Clinical Research Unit, Research Institute of McGill University Health Centre, McGill University, Montreal, Canada

Nafiseh Naderi

McGill University - Division of Experimental Medicine; Respiratory Epidemiology and Clinical Research Unit, Research Institute of McGill University Health Centre, McGill University, Montreal, Canada

Abolfazl Dehghan

Islamic Azad University (IAU)

Sanaz Azizi

Islamic Azad University (IAU)

Date Written: 2012

Abstract

This is a descriptive case report of a 30-year-old man with massive epistaxis, echymosis on arms, abnormal CBC and increased plasma urea and creatinine level (i.e. above normal range). Probably, these are as side effects of interferon beta-1a injection. This is the first report according to our literature search (Pub Med, Google scholar, ISI web of knowledge, ProQuest, MD consult, Science Direct, and SCOPUS) about interferon beta-1a related abnormal kidney function tests hereafter. Abnormal kidney function tests (i.e. increased plasma urea and creatinie level) is not a known as side effect of interferon beta-1a. This case indicates, likely potential for development of these side effects with this medication.

Keywords: Interferon beta, Side effect, Multiple sclerosis, Rebif

Suggested Citation

Tavakoli, Maryam and Mostafavi-Pour-Manshadi, Seyed-Mohammad-Yousof and Naderi, Nafiseh and Dehghan, Abolfazl and Azizi, Sanaz, Unusual Side Effects of Interferon Beta-1a in Patient with Multiple Sclerosis (2012). Mat Soc Med, 2012. Available at SSRN: https://ssrn.com/abstract=2658340

Maryam Tavakoli

Islamic Azad University (IAU) ( email )

Hamedan, Iran
Tehran, Isfahan 461-15655
Iran

Seyed-Mohammad-Yousof Mostafavi-Pour-Manshadi (Contact Author)

Respiratory Epidemiology and Clinical Research Unit, Research Institute of McGill University Health Centre, McGill University, Montreal, Canada ( email )

Montreal, Quebec
Canada

Nafiseh Naderi

McGill University - Division of Experimental Medicine ( email )

Montreal, Quebec
Canada

Respiratory Epidemiology and Clinical Research Unit, Research Institute of McGill University Health Centre, McGill University, Montreal, Canada ( email )

Abolfazl Dehghan

Islamic Azad University (IAU) ( email )

Hamedan, Iran
Tehran, Isfahan 461-15655
Iran

Sanaz Azizi

Islamic Azad University (IAU) ( email )

Hamedan, Iran
Tehran, Isfahan 461-15655
Iran

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