Gross Congenital Malformation at Birth in a Government Hospital
Indian J Public Health 2014;58:54-6, January-March 2014
3 Pages Posted: 27 Mar 2018
Date Written: January 16, 2016
A hospital-based cross-sectional study was undertaken to determine proportion of gross congenital malformation (GCMF) occurring at intramural births in a government hospital of India. Rate of GCMF was found to be 16.4/1000 consecutive singleton births (>28 weeks) with three leading malformation as anencephaly (44.68%), talipes equinovarus (17.02%) and meningomyelocele (10.63%). Higher risk of malformed births were noticed amongst un-booked (2.07%) in-comparison to booked (1.01%) mothers; women with low level of education (up to 8 years [2.14%] vs. at least 9 years of schooling [0.82%]); gravida status of at least 3 (2.69%) followed by 1 (1.43%) and 2 (1.0%) respectively; pre-term (5.13%) vs. term (0.66%); cesarean section (4.36%) versus vaginal delivery (0.62%). Mortality was significantly higher among congenitally malformed (17.35%) than normal (0.34%) newborns. Malformation was found to be slightly higher in females, giving an overall female: male ratio of 1.35:1 (P>0.05). With-in study limitation, emergence of neural tube defect as the single largest category of congenital malformation indicates maternal malnutrition (especially folic acid) that needs appropriate attention and management.
Keywords: Folic acid, Hospital, Neural tube defect, Nutrition, Natal, Ultrasound, Women, high risk mothers, abortion, neo natal mortality, birth
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