'Money Blinding' as a Solution to Biased Design and Conduct of Scientific Research
in Christopher T. Robertson & Aaron S. Kesselhein, eds., BLINDING AS A SOLUTION TO BIAS: STRENGTHENING BIOMEDICAL SCIENCE, FORENSIC SCIENCE, AND LAW (Elsevier, 2016), Forthcoming
20 Pages Posted: 3 Feb 2016
Date Written: 2016
Blinding has become an important method to prevent doctors and patients from providing biased data for biomedical research. However, when commercial interests select and fund the investigators, the overall design, conduct, and reporting of scientific research may still be biased toward suggesting products being tested are safer and more efficacious than they really are. We review some of the history around the concept of having biomedical research conducted independently of industry. One approach would be to have companies fund the research on their products but have an intermediary select independent investigators to design and conduct the research. This solution can be considered a form of “blinding.” We explore the potential benefits and limitations of money blinding. We then examine steps that various actors can take to promote the adoption of money blinding. Finally, we explore some ways that biomedical journals or the federal government could cause blinding to be adopted.
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