Green Analytical Chemistry, Opportunities for Pharmaceutical Quality Control
28 Pages Posted: 8 Jul 2017
Date Written: June 6, 2016
This review article summarizes the opportunities for utilizing the green analytical chemistry (GAC) techniques and principles in the field of quality control (Q.C) of the pharmaceuticals. Green analytical chemistry is considered a branch of the green chemistry which is based on principles overlap with the sustained development ultimate goals. General definitions of quality and quality control, principles of Green Analytical Chemistry, proposals for greener sample pre-treatment, and greener chromatographic method of analysis to be applied in QC laboratories are herein discussed. The main goal is achieving more eco- friendly analysis in QC laboratories through different strategies and techniques replace the toxic reagents, and to modify or replace analytical methods and/or techniques with safer ones, making it possible to dramatically reduce the amounts of reagents consumed and waste generated.
General definitions for quality and quality control:
There are Several definitions of the term “quality”, yet one of them is of top importance to the perception of “Managing for Quality” concept. This definition describes product quality as “those features of products which meet customer needs and the freedom from deficiencies hereby provide customer satisfaction”. Managing for quality makes extensive use of three managerial processes:
1- Quality planning;
2- Quality control;
3- Quality improvement.
Keywords: sample preparation, Green sample preparation, Green chromatographic techniques, Benign Solvents
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