Progress in Human Embryonic Stem Cell Research in the United States between 2001 and 2010

Published in PLoS One, 10 (3), 2015

Rotman School of Management Working Paper No. 2883414

8 Pages Posted: 12 Dec 2016

See all articles by Keyvan Vakili

Keyvan Vakili

London Business School

Anita M. McGahan

University of Toronto - Rotman School of Management

Rahim Rezaie

University of Toronto

Will Mitchell

University of Toronto

Abdallah S. Daar

University of Toronto

Date Written: February 1, 2015

Abstract

On August 9th, 2001, the federal government of the United States announced a policy restricting federal funds available for research on human embryonic stem cell (hESCs) out of concern for the “vast ethical mine fields” associated with the creation of embryos for research purposes. Until the policy was repealed on March 9th, 2009, no U.S. federal funds were available for research on hESCs extracted after August 9, 2001, and only limited federal funds were available for research on a subset of hESC lines that had previously been extracted. This paper analyzes how the 2001 U.S. federal funding restrictions influenced the quantity and geography of peer-reviewed journal publications on hESC. The primary finding is that the 2001 policy did not have a significant aggregate effect on hESC research in the U.S. After a brief lag in early 2000s, U.S. hESC research maintained pace with other areas of stem cell and genetic research. The policy had several other consequences. First, it was tied to increased hESC research funding within the U.S. at the state level, leading to concentration of related activities in a relatively small number of states. Second, it stimulated increased collaborative research between US-based scientists and those in countries with flexible policies toward hESC research (including Canada, the U.K., Israel, China, Spain, and South Korea). Third, it encouraged independent hESC research in countries without restrictions.

Keywords: science, scientific progress, funding policy, collaboration, human embryonic stem cells, stem cells

Suggested Citation

Vakili, Keyvan and McGahan, Anita M. and Rezaie, Rahim and Mitchell, Will and Daar, Abdallah S., Progress in Human Embryonic Stem Cell Research in the United States between 2001 and 2010 (February 1, 2015). Published in PLoS One, 10 (3), 2015, Rotman School of Management Working Paper No. 2883414, Available at SSRN: https://ssrn.com/abstract=2883414

Keyvan Vakili (Contact Author)

London Business School ( email )

Sussex Place
Regent's Park
London, London NW1 4SA
United Kingdom

Anita M. McGahan

University of Toronto - Rotman School of Management ( email )

105 St. George Street
Toronto, Ontario M5S 3E6 M5S1S4
Canada
416-978-6188 (Phone)

Rahim Rezaie

University of Toronto ( email )

Toronto, Ontario M5S 3G8
Canada

Will Mitchell

University of Toronto ( email )

Toronto, Ontario M5S 3G8
Canada

Abdallah S. Daar

University of Toronto ( email )

Toronto, Ontario M5S 3E6 M5S 3G8
Canada

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