Effects of Gemini Surfactants on Model Phosphatidylcholine Bilayers in the Fluid Lamellar Phase

Science Direct Working Paper No S1574-0331(04)70560-3

6 Pages Posted: 14 Jun 2017 Last revised: 6 Jan 2018

See all articles by Martina Dubnickova

Martina Dubnickova

Comenius University - Faculty of Pharmacy

S. Yaradaikin

Joint Institute for Nuclear Research - Frank Laboratory of Neutron Physics

Ivan Lacko

Comenius University - Department of Chemical Theory of Drugs, Faculty of Pharmacy

Ferdinand Devínsky

Univerzita Komenského v Bratislave

V. Gordeliy

Joint Institute for Nuclear Research - Frank Laboratory of Neutron Physics

Pavol Balgavy

Comenius University - Department of Physical Chemistry of Drugs, Faculty of Pharmacy

Date Written: January 2003

Abstract

The influence of 1,4-butanediamonium-N,N’-dialkyl-N,N,N’,N’-tetramethyl dibromides (CmA, m=7-16 is the number of alkyl carbons) on the egg yolk phosphatidylcholine (EYPC) bilayer thickness and lipid surface area at the bilayer – aqueous phase interface is studied using x-ray diffraction on fluid lamellar CmA+EYPC+HO phases. At the constant CmA:EYPC=0.4 and HO:EYPC=18 molar ratios, the bilayer thickness and the lipid surface area show nonlinear dependencies on the alkyl chain length m with the extremes at m=9.

Keywords: Physical Chemistry > Colloid and Surface Chemistry, physchem/0301007

Suggested Citation

Dubnickova, Martina and Yaradaikin, S. and Lacko, Ivan and Devínsky, Ferdinand and Gordeliy, V. and Balgavy, Pavol, Effects of Gemini Surfactants on Model Phosphatidylcholine Bilayers in the Fluid Lamellar Phase (January 2003). Science Direct Working Paper No S1574-0331(04)70560-3, Available at SSRN: https://ssrn.com/abstract=2979002

Martina Dubnickova (Contact Author)

Comenius University - Faculty of Pharmacy ( email )

Bratislava, 832 32
Slovakia

S. Yaradaikin

Joint Institute for Nuclear Research - Frank Laboratory of Neutron Physics

Joliot-Curie str. 6
Dubna, Moscow 141980
Russia

Ivan Lacko

Comenius University - Department of Chemical Theory of Drugs, Faculty of Pharmacy

Odbojarov 2
83232 Bratislava
Slovakia

Ferdinand Devínsky

Univerzita Komenského v Bratislave ( email )

Slovakia

V. Gordeliy

Joint Institute for Nuclear Research - Frank Laboratory of Neutron Physics

Joliot-Curie str. 6
Dubna, Moscow 141980
Russia

Pavol Balgavy

Comenius University - Department of Physical Chemistry of Drugs, Faculty of Pharmacy ( email )

Odboja ´rov 10
Bratislava, SK-832 32
Slovakia

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