Pregnancy Outcome Following Swim Up Preparation of Both Fresh and Cryopreserved Spermatozoa

Scientific Research and Essay Vol. 1 (3), December, 2006

5 Pages Posted: 16 Aug 2017 Last revised: 20 Aug 2017

See all articles by Lukeman Shittu

Lukeman Shittu

Jireh Laboratories International LLC; Houston Community College, Department of Biology; University of Abuja, Department of Anatomical Sciences; Benue State University, Department of Anatomy; Lagos State University - Department of Anatomy

O Babalola

LASUCOM

O Adesanya

Lagos State University

P Jewo

LASUCOM

A Oyewopo

Lagos State University

O.A. Ashiru

Lagos State University - Department of Anatomy

Date Written: December 1, 2006

Abstract

This study was designed to assess the impact of swim up preparation of both fresh and cryopreserved sperm on the pregnancy outcome in a private fertility centre in Lagos. A cross-sectional prospective analysis of 34 asthenozoospermic semen samples of men whose wives were undergoing assisted reproduction was studied. The basic semen parameters comprising of the volume, count, and motility of the sperm before and after swim up preparations with pregnancy outcome were measured. For fresh semen (n = 28, mean age = 37.0 ± 1.1 years, mean volume = 2.16 ± 0.1 ml), the sperm count decreased significantly (p<0.01) from the pre swim up value of 55.4 ± 3.10 to 44.6 ± 3.20 x 106/ml post swim up. While, the motility increased significantly (p<0.01) from 39.6 ± 3.84 to 58.5 ± 4.29%. The percentage pregnancy outcome in the fresh semen was 66%. For the cryopreserved semen (n = 6, mean age = 41.0 ± 5.4 years, mean volume = 1.8 ± 0.1 ml), the sperm count decreased significantly (p<0.01) from pre swim up value of 35.6 ± 3.03 to 33.3 ± 4.33 x 106/ml post swim up, while the motility increased significantly (p<0.01) from 25.1 ± 4.01 to 32.8 ± 6.18%. The pregnancy outcome of cryopreserved was 30%. The pregnancy outcome was higher with fresh than the cryopreserved semen. However, the motility was a significant indicator for the successful outcome. Swim up procedure improve the motility of both cryopreserved and fresh semen with a better pregnancy outcome in this study.

Keywords: Swim-up, Cryopreserved sperm, Fresh sperm, Asthenozoopermia, Sperm motility, Sperm count, pregnancy

JEL Classification: I10

Suggested Citation

Shittu, Lukeman and Babalola, O and Adesanya, O and Jewo, P and Oyewopo, A and Ashiru, O.A., Pregnancy Outcome Following Swim Up Preparation of Both Fresh and Cryopreserved Spermatozoa (December 1, 2006). Scientific Research and Essay Vol. 1 (3), December, 2006. Available at SSRN: https://ssrn.com/abstract=3017042

Lukeman Shittu (Contact Author)

Jireh Laboratories International LLC ( email )

P.O.BOX 1813
ALIEF, TX HOUSTON 77411
United States
346-322-5042 (Phone)

HOME PAGE: http://linkedin.com/in/drlukemanjosephshittu

Houston Community College, Department of Biology ( email )

3100 Main Street
Houston, TX Harris County 77002
United States

HOME PAGE: http://linkedin.com/in/drlukemanjosephshittu

University of Abuja, Department of Anatomical Sciences ( email )

Airport Road Giri
Gwagalada
F.C.T, West Africa 00234
Nigeria

HOME PAGE: http://linkedin.com/in/drlukemanjosephshittu

Benue State University, Department of Anatomy ( email )

Along Gboko Rd, P.M.B.102119 Makurdi-Gboko Rd
Makurdi, 97001
Nigeria

HOME PAGE: http://linkedin.com/in/drlukemanjosephshittu

Lagos State University - Department of Anatomy ( email )

Ikeja, Lagos
Nigeria

O Babalola

LASUCOM ( email )

Lagos/bagagry express road lagos nigeria.
PMB 0001 LASU OJO Lagos Nigeria
Lagos, 234
Nigeria

O Adesanya

Lagos State University ( email )

Lagos/bagagry express road lagos nigeria.
PMB 0001 LASU OJO Lagos Nigeria
Lagos, 234
Nigeria

P Jewo

LASUCOM ( email )

Lagos/bagagry express road lagos nigeria.
PMB 0001 LASU OJO Lagos Nigeria
Lagos, 234
Nigeria

A Oyewopo

Lagos State University ( email )

Lagos/bagagry express road lagos nigeria.
PMB 0001 LASU OJO Lagos Nigeria
Lagos, 234
Nigeria

O.A. Ashiru

Lagos State University - Department of Anatomy

Ikeja, Lagos
Nigeria

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