Nano-Diamond Hybrid Materials for Structural Biomedical Application

American Journal of Biochemistry and Biotechnology, Volume 13, Issue 1, Pages 34-41 (2016)

8 Pages Posted: 28 Nov 2017

See all articles by Raffaella Aversa

Raffaella Aversa

Advanced Material Lab - Department of Architecture and Industrial Design

Relly Victoria Petrescu

Polytechnic University of Bucharest - ARoTMM-IFToMM

Antonio Apicella

Advanced Material Lab - Department of Architecture and Industrial Design

Florian Ion Petrescu

Polytechnic University of Bucharest - ARoTMM-IFToMM

Date Written: November 22, 2017

Abstract

The development of new diamond based bio-mechanically active hybrid nano-structured scaffolds for cartilage cells tissue engineering are proposed in this study. Innovative tissue engineering biomimetic materials based on hydrogel have shown attractive physical, biological and mechanical properties in several biomedical applications. A highly biocompatible novel hybrid material based on nanodiamonds and hydrophilic poly-(hydroxyl-ethyl-methacrylate) (pHEMA) is proposed. The aim of this paper is to describe the chemical and analytical procedures for the preparation of nanofilled hybrid composites possessing biomimetic, osteoconductive and osteoinductivity properties that can be useful in the design of bio-mechanically active innovative bone scaffolding systems for stem cell differentiation and growth. A more rigid and rubber transparent hybrid nano-composites are predicted to posses improved mechanical strength overwhelming one of the major weaknesses of hydrogels, which is due their poor mechanical characteristics, for applications in biomedical structural application.

Note: © 2017 Raffaella Aversa, Relly Victoria V. Petrescu, Antonio Apicella and Florian Ion T. Petrescu. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Suggested Citation

Aversa, Raffaella and Petrescu, Relly Victoria and Apicella, Antonio and Petrescu, Florian Ion, Nano-Diamond Hybrid Materials for Structural Biomedical Application (November 22, 2017). American Journal of Biochemistry and Biotechnology, Volume 13, Issue 1, Pages 34-41 (2016). Available at SSRN: https://ssrn.com/abstract=3076190

Raffaella Aversa

Advanced Material Lab - Department of Architecture and Industrial Design ( email )

81031 Aversa (CE)
Italy

Relly Victoria Petrescu

Polytechnic University of Bucharest - ARoTMM-IFToMM ( email )

Romania

Antonio Apicella

Advanced Material Lab - Department of Architecture and Industrial Design ( email )

81031 Aversa (CE)
Italy

Florian Ion Petrescu (Contact Author)

Polytechnic University of Bucharest - ARoTMM-IFToMM ( email )

Romania

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