How Translational Medicine Is Progressively Redefining Healthcare: From Bench to Bedside, the Patient Is the Bedrock of Translational Research

Posted: 21 Dec 2017

Date Written: December 19, 2017

Abstract

Translational medicine or translation research is an umbrella term that covers specific research in biological sciences whose main goal is to increase human life expectancy by keeping us healthy (from better ideas to better health). It’s synonymous with translational medical science, disease-targeted research, or evidence-based research. Translation research is particular because of its bidirectional nature. It’s commonly called the B2B approach or bench to bedside approach because it incorporates clinical skills and observations as well as scientific hypotheses utilized by researchers in the laboratories. The whole concept functions in a loop: bench to bedside and back. It translates knowledge, skills, or science from one place to another not only by focusing on the traditional 4P-Medicine – personalization, prevention, prediction, and participation – but also by taking into consideration another 3 Ps: providing (staff training), preemptive (research and development), and point of care (making sure that healthcare can be given anytime anywhere). Because of that, translational medicine can be viewed as a paradigm shift. This revolutionary concept shows how research discoveries can translate into effective therapies… Moreover, the understanding of disease pathology and preclinical models (their availability, their relevance to the disease and their translatability are considered key focus of modern translation research or translational medicine. Disease pathology may differ from one individual to the next. Researchers in the biological and the medical fields understand that. Thus, today, pharmacogenomics or personalized medicine is a field in the making and is set to revolutionized how patients are treated because the one size fits all approach is becoming more and more a thing of the past. Disease pathology also prompts researchers to consider our genetic makeups or our DNA first thing when trying to invent drugs or medical techniques likely to improve or enhance life expectancy.

Keywords: Translational Research, Translational Medicine, Bench to Bedside

Suggested Citation

Dufour, Fritz, How Translational Medicine Is Progressively Redefining Healthcare: From Bench to Bedside, the Patient Is the Bedrock of Translational Research (December 19, 2017). Available at SSRN: https://ssrn.com/abstract=3090737 or http://dx.doi.org/10.2139/ssrn.3090737

Fritz Dufour (Contact Author)

Independent ( email )

New York, NY

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