Understanding Medication Nonadherence from Social Media: A Sentiment-Enriched Deep Learning Approach

60 Pages Posted: 28 Dec 2017 Last revised: 27 Oct 2018

See all articles by Jiaheng Xie

Jiaheng Xie

University of Arizona - Department of Management Information Systems

Xiao Liu

University of Utah

Daniel Dajun Zeng

University of Arizona - Department of Management Information Systems

Xiao Fang

Lerner College of Business and Economics, University of Delaware

Date Written: December 21, 2017

Abstract

Medication nonadherence (MNA) refers to the behavior when patients do not take medications as prescribed. Adverse health outcomes of MNA cost the U.S. healthcare systems $290 billion annually. Understanding MNA and preventing harmful outcomes are an urgent goal for researchers, practitioners, and the pharmaceutical industry. Past years have witnessed rising patient engagement in social media, making it a cost-efficient and heterogeneous data source that can complement and deepen the understanding of MNA. Yet, such dataset is untapped in existing MNA studies. We present the first study to identify MNA reasons from health social media. Health social media analytics studies face technical challenges such as varied patient vocabulary and little relevant information. We develop the Sentiment-Enriched DEep Learning (SEDEL) to address these challenges. We evaluate SEDEL on 53,180 reviews about 180 drugs and achieve a precision of 87.29%, a recall of 93.27%, and an F1 score of 90.18%. SEDEL significantly outperforms state-of-the-art baseline models. Nine categories of MNA reasons are identified. This study contributes to IS research in two aspects. First, we formally define the MNA reason mining problem and devise a novel deep-learning-based approach; second, our results provide direct implications for healthcare practitioners to understand patient behaviors and design interventions.

Keywords: Sentiment-enriched deep learning (SEDEL), text mining, health analytics, medication nonadherence, precision medicine

Suggested Citation

Xie, Jiaheng and Liu, Xiao and Zeng, Daniel Dajun and Fang, Xiao, Understanding Medication Nonadherence from Social Media: A Sentiment-Enriched Deep Learning Approach (December 21, 2017). Available at SSRN: https://ssrn.com/abstract=3091923 or http://dx.doi.org/10.2139/ssrn.3091923

Jiaheng Xie (Contact Author)

University of Arizona - Department of Management Information Systems ( email )

AZ
United States

Xiao Liu

University of Utah ( email )

1645 E. Campus Center
Salt Lake City, UT 84112
United States

Daniel Dajun Zeng

University of Arizona - Department of Management Information Systems ( email )

AZ
United States

Xiao Fang

Lerner College of Business and Economics, University of Delaware ( email )

Newark, DE 19716
United States

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