Gene-Environment Interactions and the Genetic Epidemiology of Obesity: Correlates for Preventative Medicine

Journal of Obesity and Metabolic Disorders, 1(1), (2018, August), 25-28

4 Pages Posted: 28 Sep 2018

See all articles by Brian P. Mangum

Brian P. Mangum

Fiji National University (FNU); College of Micronesia - Federated States of Micronesia; Xavier University - School of Medicine

Tamara Mangum

Fiji National University (FNU) - College of Medicine, Nursing, and Health Sciences

Date Written: August 1, 2018

Abstract

As obesity rates continue to rise in the United States, and throughout the world, the role of genetics is playing an increasingly prominent role in understanding the underlying causes of this disease. Numerous studies have been undertaken to understand the role of genetics in obesity, and to identify those candidate genes which are associated with such. This has resulted in studies showing various degrees of association between obesity-related morphological characteristics, including increased body mass index, hip circumference and height/weight ratios, and genetic variants, particularly in the FTO and PFKP genes. The true value of these studies is not in their causal explanations for obesity, but rather in the importance of understanding the role of the gene-environment interaction, and the way in which such can be used to develop integrated public health prevention programs for obesity which are based upon lifestyle risk factors for such.

Keywords: obesity, genetic epidemiology, public health, gene-environment interaction, prevention

Suggested Citation

Mangum, Brian P. and Mangum, Tamara, Gene-Environment Interactions and the Genetic Epidemiology of Obesity: Correlates for Preventative Medicine (August 1, 2018). Journal of Obesity and Metabolic Disorders, 1(1), (2018, August), 25-28, Available at SSRN: https://ssrn.com/abstract=3246463 or http://dx.doi.org/10.2139/ssrn.3246463

Brian P. Mangum (Contact Author)

Fiji National University (FNU) ( email )

P.O.Box 7222
Fiji

College of Micronesia - Federated States of Micronesia ( email )

PO Box 159
Kolonia, Pohnpei, 96941
Micronesia

Xavier University - School of Medicine ( email )

NY
United States

Tamara Mangum

Fiji National University (FNU) - College of Medicine, Nursing, and Health Sciences ( email )

P.O.Box 7222
Fiji

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