Mechanisms and Treatment of Chemotherapy-Induced Cognitive Impairment ('Chemobrain')

22 Pages Posted: 19 Nov 2018

Date Written: October 26, 2018


Chemotherapy-induced cognitive impairment (CICI; also called “cancer-related cognitive impairment,” “cancer-related cognitive dysfunction,” or “chemobrain”) is a widely recognized consequence of cancer treatment, with potential to disrupt the daily and occupational lives of survivors for a period of time. This review covers what has been published on the mechanisms involved in, and treatment approaches explored to date for, CICI.

Keywords: Chemobrain, Chemotherapy, CICI, CRCI, MESNA, Resveratrol, FOLFOX, Mitoxantrone, Leucovorin, Cyclophosphamide, Everolimus, Temozolomide, Procarbazine, Mitomycin C, ApoE4, Oxaliplatin, Mithramycin, Adriamycin, Cisplatin, Carboplatin, Sunitinib, 5-Fluorouracil, Paclitaxel, Docetaxel, Methotrexate

Suggested Citation

Suuberg, Alessandra, Mechanisms and Treatment of Chemotherapy-Induced Cognitive Impairment ('Chemobrain') (October 26, 2018). Available at SSRN: or

Alessandra Suuberg (Contact Author)

Independent ( email )

No Address Available

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