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Prevalence of Hepatitis B and C Virus Infection at a Tertiary Care Hospital in Pakistan

25 Pages Posted: 8 Mar 2019

See all articles by Muhammad Imran Khan

Muhammad Imran Khan

University of Science and Technology of China (USTC) - Medical Building

Ahsan Kazmi

Isra University

Fadia Kalsoom

Aga Khan University

Muzamal Bashir

Shaheed Benazir Bhutto University

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Abstract

Introduction: The prevalence of Hepatitis B and C virus infections is high and the guidelines are not sufficiently effective to control prevalence. There are some countries and areas where no prevalence data for viral hepatitis is available for hospitalized patients. This work focuses on the prevalence of Hepatitis B and C virus infections in hospitalized patients and outdoor attendees.  

Methods: This was a descriptive cross-sectional observational study for seven months conducted at Benazir Bhutto Hospital Rawalpindi Pakistan that included Hospitalized patients and outdoor attendees referred by the Physician/Surgeon for Viral Hepatitis screening. Three ml of venous blood collected from 2003 subjects and processed to investigate infection by ELISA.  

Results: The highest prevalence of HBV was 4.2% in the patients of Surgery and Medicine and the lowest in Orthopedics, Urology, Gynecology and Obstetrics, Pediatrics, Intensive Care Unit, Ear Throat and Nose, Eye  >0.001%. The highest prevalence of Hepatitis C virus was in Medicine 22.90% and lowest was in Pediatrics >0.001%. The highest prevalence of HBV was 4.55% in the age range of 61-75 and lowest >0.001% in 76-90 years. Age group 46-60 years showed the highest 19.07% and 16-30 years the lowest 6.44% prevalence of Hepatitis C virus infection. Observed HBV-positive participants were 60.78% males and 39.22% females. While among participants Hepatitis C Virus (Positive) 50.90% males and 49.10% were females.  

Conclusions: The prevalence of HBV and HCV is very high. There should be more effective policies operation.

Funding Statement: This study was partially supported by BBH Rawalpindi, which was limited to available resources of the Hospital. [Letter No.6/BBH. Dated 16.06.2016]. No funding as a separate grant was received for this study.

Declaration of Interests: The authors declare no competing interest.

Ethics Approval Statement: The study was approved by the Ethical Committe at Benazir Bhutto Hospital, Rawalpindi.

Keywords: Hepatitis B; Hepatitis C; Indoor patients; Outdoor patients; Prevalence

Suggested Citation

Khan, Muhammad Imran and Kazmi, Ahsan and Kalsoom, Fadia and Bashir, Muzamal, Prevalence of Hepatitis B and C Virus Infection at a Tertiary Care Hospital in Pakistan (February 2, 2019). Available at SSRN: https://ssrn.com/abstract=3328663

Muhammad Imran Khan (Contact Author)

University of Science and Technology of China (USTC) - Medical Building ( email )

Hefei, Anhui Province
China

Ahsan Kazmi

Isra University

Hyderabad, Sindh
Pakistan

Fadia Kalsoom

Aga Khan University

Stadium Road, P.O. Box 3500
Nairobi, 74800
Kenya

Muzamal Bashir

Shaheed Benazir Bhutto University

Sheringal
Dir, Khyber Pakhtunkhwa
Pakistan

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