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The Global Trends in Incidence of Different Oral Disorders: Results from the Global Burden of Disease Study 2017 and the Impact on the Prevention

62 Pages Posted: 4 Apr 2019

See all articles by Chuan-Yu Hu

Chuan-Yu Hu

Xi'an Jiaotong University (XJTU) - Clinical Research Center; Huazhong University of Science and Technology (Formerly Tongi Medical University) - Tongji Hospital

Wei-Ming Wang

Central South University - Xiangya Hospital; Xi'an Jiaotong University (XJTU) - Clinical Research Center

Jun Zhang

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital; Xi'an Jiaotong University (XJTU) - School of Public Health; Baoji Centre Hospital

Hai-Rong He

Xi'an Jiaotong University (XJTU) - Clinical Research Center

Yuan-Jie Li

Xi'an Jiaotong University (XJTU) - School of Basic Medical Sciences

Zhen-Hu Ren

Xi'an Jiaotong University (XJTU) - Clinical Research Center; Shanghai Jiao Tong University (SJTU) - Department of Oral Maxillofacial-Head and Neck Oncology

Jun Lyu

Xi'an Jiaotong University (XJTU) - Clinical Research Center; Xi'an Jiaotong University (XJTU) - School of Public Health; Institute of Evidence-Based Medicine and Knowledge Translation

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Abstract

Background: Oral disorders(OD) are the most common diseases in the world, ranking third in incidence. The etiology of OD is diverse, and there is little research on the incidence trend of different OD in different regions. Therefore, we aimed to determine the incidence pattern and time trend of OD.  

Methods: We collected detailed information on 4 OD between 1990 and 2017 from the Global Burden of Disease Study. Estimated annual percentage change (EAPC) in OD, age-standardized incidence rate (ASR), and estimates based on gender, region and etiology were calculated to quantify the temporal trends in OD.  

Findings: Globally, the incidence cases of OD increased 31.4%, from 2.74 billion in 1990 to 3.60 billion in 2017. The overall EAPC decreased 0.04% (95% CI -0.05% - -0.02%). The EAPC of Periodontal diseases (PD) increased 0.18 (95% CI 0.15-0.21). The EAPC of caries of permanent teeth remained stable, while the ASR of CDT and edentulism and severe tooth loss (EST) gradually decreased, with corresponding EAPC of -0.13 (95% CI -0.15 - -0.11) and -0.14 (95% CI -0.19- -0.09). OD have been observed to have the most significant growth in Belgium and Spain, while a most significant decline in Nigeria. PD showed a downward trend in the areas with high Socio-demographic Index (SDI) but an upward trend in the other four. EST have declined significantly in countries with a high SDI.  

Interpretation: OD are an important public health problem in the world. The rising incidence of PD cannot be ignored. We observed that the trend of OD incidence is closely related to the value of the national SDI. What is worth noting, Nigeria has the best control of OD incidence worldwide. More targeted and specific strategies should be developed in some countries to reduce the incidence of OD.  

Funding Statement: This study was supported by the National Social Science Foundation of China (No.16BGL183) and the Foundation of Health Commission of Hubei, China (No. WJ2017M072)

Declaration of Interest: The author reports no conflicts of interest in this work.

Keywords: GBD; oral disorders; incidence; EAPC

Suggested Citation

Hu, Chuan-Yu and Wang, Wei-Ming and Zhang, Jun and He, Hai-Rong and Li, Yuan-Jie and Ren, Zhen-Hu and Lyu, Jun, The Global Trends in Incidence of Different Oral Disorders: Results from the Global Burden of Disease Study 2017 and the Impact on the Prevention (03/28/2019 14:52:53). Available at SSRN: https://ssrn.com/abstract=3362452

Chuan-Yu Hu

Xi'an Jiaotong University (XJTU) - Clinical Research Center

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Tongji Hospital

1239 Siping Road
Shanghai, 200092
China

Wei-Ming Wang

Central South University - Xiangya Hospital

Hunan Sheng, 410008
China

Xi'an Jiaotong University (XJTU) - Clinical Research Center

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Jun Zhang

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Xi'an Jiaotong University (XJTU) - School of Public Health

China

Baoji Centre Hospital

Baoji, 721008
China

Hai-Rong He

Xi'an Jiaotong University (XJTU) - Clinical Research Center

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Yuan-Jie Li

Xi'an Jiaotong University (XJTU) - School of Basic Medical Sciences ( email )

China

Zhen-Hu Ren

Xi'an Jiaotong University (XJTU) - Clinical Research Center ( email )

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Shanghai Jiao Tong University (SJTU) - Department of Oral Maxillofacial-Head and Neck Oncology ( email )

Shanghai, 200011
China

Jun Lyu (Contact Author)

Xi'an Jiaotong University (XJTU) - Clinical Research Center ( email )

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Xi'an Jiaotong University (XJTU) - School of Public Health ( email )

China

Institute of Evidence-Based Medicine and Knowledge Translation ( email )

China

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