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Lab on a Tip: Applications of Functional Atomic Force Microscopy for the Study of Electrical Properties in Biology

23 Pages Posted: 30 May 2019 First Look: Accepted

See all articles by Ling-Zhi Cheong

Ling-Zhi Cheong

Ningbo University - College of Food and Pharmaceutical Sciences

Weidong Zhao

Chinese Center for Disease Control and Prevention - National Institute of Nutrition and Health

Shuang Song

Chinese Center for Disease Control and Prevention - National Institute of Nutrition and Health

Cai Shen

Chinese Academy of Sciences (CAS) - Ningbo Institute of Material Technology and Engineering

Abstract

Electrical properties, such as charge propagation, dielectrics, surface potentials, conductivity, and piezoelectricity, play crucial roles in biomolecules, biomembranes, cells, tissues, and other biological samples. However, characterizing these electrical properties in delicate biosamples is challenging. Atomic Force Microscopy (AFM), the so called "Lab on a Tip" is a powerful and multifunctional approach to quantitatively study the electrical properties of biological samples at the nanometer level. Herein, the principles, theories, and achievements of various modes of AFM in this area have been reviewed and summarized.

Keywords: Atomic Force Microscopy, Electrical properties, Biology

Suggested Citation

Cheong, Ling-Zhi and Zhao, Weidong and Song, Shuang and Shen, Cai, Lab on a Tip: Applications of Functional Atomic Force Microscopy for the Study of Electrical Properties in Biology (May 30, 2019). Available at SSRN: https://ssrn.com/abstract=3396278

Ling-Zhi Cheong (Contact Author)

Ningbo University - College of Food and Pharmaceutical Sciences

China

Weidong Zhao

Chinese Center for Disease Control and Prevention - National Institute of Nutrition and Health

155 Changbai Road
Changping District
Beijing, Changping District 102206
China

Shuang Song

Chinese Center for Disease Control and Prevention - National Institute of Nutrition and Health

155 Changbai Road
Changping District
Beijing, Changping District 102206
China

Cai Shen

Chinese Academy of Sciences (CAS) - Ningbo Institute of Material Technology and Engineering ( email )

Ningbo, 315201
China

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