puc-header

Multiplexing of Self and Other Information in Hippocampal Ensembles

66 Pages Posted: 4 Jun 2019 Sneak Peek Status: Review Complete

See all articles by Jeroen J. Bos

Jeroen J. Bos

University of Amsterdam - Swammerdam Institute for Life Sciences

Martin Vinck

University of Amsterdam - Swammerdam Institute for Life Sciences

Pietro Marchesi

University of Amsterdam - Swammerdam Institute for Life Sciences

Amos Keestra

University of Amsterdam - Swammerdam Institute for Life Sciences

Laura A. van Mourik-Donga

University of Amsterdam - Swammerdam Institute for Life Sciences

Jadin Jackson

Medtronic (Minneapolis)

Paul Verschure

Barcelona Institute of Science and Technology (BIST)

Cyriel Pennartz

University of Amsterdam - Swammerdam Institute for Life Sciences

More...

Abstract

The hippocampus is essential for spatial navigation and memory and harbors place cells, coding an animal’s location in space. The hippocampus has also been suggested to code social information, such as about the spatial position of conspecifics. "Social place cells" have been reported for tasks where an observer mimics the behavior of a demonstrator. We examined whether hippocampal neurons may encode the behavior of a minirobot, however without requiring the animal to mimic it. Rather than finding social place cells, we observed that robot behavioral patterns modulate place fields coding animal position. During task performance, the rat’s own positions correlated with robot movements. We found that hippocampal ensembles coded information about robot movement patterns, even when correcting for rat position. Interneurons were more informative on robot movements than principal cells. In conclusion, when the animal’s own behavior is conditional on external agents, the hippocampus multiplexes information about self and others.

Keywords: place cells, mirror neurons, tetrode, population coding, mutual information, information theory, decoding, robot, robotics, social neuroscience

Suggested Citation

Bos, Jeroen J. and Vinck, Martin and Marchesi, Pietro and Keestra, Amos and van Mourik-Donga, Laura A. and Jackson, Jadin and Verschure, Paul and Pennartz, Cyriel, Multiplexing of Self and Other Information in Hippocampal Ensembles (June 4, 2019). CELL-REPORTS-D-19-02025. Available at SSRN: https://ssrn.com/abstract=3398593 or http://dx.doi.org/10.2139/ssrn.3398593
This is a paper under consideration at Cell Press and has not been peer-reviewed.

Jeroen J. Bos

University of Amsterdam - Swammerdam Institute for Life Sciences

Netherlands

Martin Vinck

University of Amsterdam - Swammerdam Institute for Life Sciences ( email )

Netherlands

Pietro Marchesi

University of Amsterdam - Swammerdam Institute for Life Sciences ( email )

Netherlands

Amos Keestra

University of Amsterdam - Swammerdam Institute for Life Sciences ( email )

Netherlands

Laura A. Van Mourik-Donga

University of Amsterdam - Swammerdam Institute for Life Sciences ( email )

Netherlands

Jadin Jackson

Medtronic (Minneapolis) ( email )

710 Medtronic Parkway
Minneapolis, MN 55432-5604
United States

Paul Verschure

Barcelona Institute of Science and Technology (BIST) ( email )

Carrer del Comte d’Urgell 187
Building 12 (BIST)
Barcelona, 08036
Spain

Cyriel Pennartz (Contact Author)

University of Amsterdam - Swammerdam Institute for Life Sciences ( email )

Netherlands

Click here to go to Cell.com

Go to Cell.com

Paper statistics

Abstract Views
269
Downloads
16