Cell Pyroptosis, a Potential Pathogenic Mechanism of 2019-nCoV Infection

7 Pages Posted: 29 Jan 2020 Last revised: 5 Feb 2020

See all articles by Ming Yang

Ming Yang

Department of Ophthalmology, Li Ka Shing Faculty of Medicine, The University of Hong Kong

Date Written: January 29, 2020

Abstract

2019-nCoV is a novel coronavirus named in 2019. The number of people suffering from the virus kept increasing from China to the world. The initial infection characters of 2019-nCoV has been reported, including the symptoms and blood test results. Cell pyroptosis is a novel inflammatory form of programmed cell death, which has been largely studied recently. Here we noted that some of the 2019-nCoV results could be matched to the cell pyroptosis. This paper is aimed to discuss the relationship between 2019-nCoV infection and cell pyroptosis and put forward a potential hypothesis.

Note: Funding: The authors did not receive grants for this study Declaration of Interest: The author declared there is no conflict of interest.

Keywords: 2019-nCoV, Pneumonia, Leucopenia, Lymphopenia, Cell Pyroptosis

Suggested Citation

Yang, Ming, Cell Pyroptosis, a Potential Pathogenic Mechanism of 2019-nCoV Infection (January 29, 2020). Available at SSRN: https://ssrn.com/abstract=3527420 or http://dx.doi.org/10.2139/ssrn.3527420

Ming Yang (Contact Author)

Department of Ophthalmology, Li Ka Shing Faculty of Medicine, The University of Hong Kong ( email )

Room 406, HKJC BIR Buildling
No.5 Sassoon Rd, Hong Kong Island
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