Cell Pyroptosis, a Potential Pathogenic Mechanism of 2019-nCoV Infection

Abstract

2019-nCoV is a novel coronavirus named in 2019. The number of people suffering from the virus kept increasing from China to the world. The initial infection characters of 2019-nCoV has been reported, including the symptoms and blood test results. Cell pyroptosis is a novel inflammatory form of programmed cell death, which has been largely studied recently. Here we noted that some of the 2019-nCoV results could be matched to the cell pyroptosis. This paper is aimed to discuss the relationship between 2019-nCoV infection and cell pyroptosis and put forward a potential hypothesis.

Note: Funding: The authors did not receive grants for this study Declaration of Interest: The author declared there is no conflict of interest.

Keywords: 2019-nCoV, Pneumonia, Leucopenia, Lymphopenia, Cell Pyroptosis