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Novel Coronavirus (2019-nCoV) Outbreak; A Systematic Review for Published Papers

23 Pages Posted: 13 Feb 2020

See all articles by Adel Al-Gheethi

Adel Al-Gheethi

Universiti Tun Hussein Onn Malaysia (UTHM) - Micropollutant Research Centre (MPRC)

Efaq Noman

Taiz University - Department of Applied Microbiology

Qais Ali Al-Maqtari

Jiangnan University - State Key Laboratory of Food Science and Technology

Kamal Hezam

Taiz University - Department of Applied Microbiology

Radin Mohamed

Universiti Tun Hussein Onn Malaysia (UTHM) - Micropollutant Research Centre (MPRC)

Balkis Talip

Universiti Tun Hussein Onn Malaysia (UTHM) - Faculty of Applied Sciences and Technology

Norli Ismail

Universiti Sains Malaysia (USM) - Environmental Technology Division

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Abstract

The novel coronavirus (2019-nCoV) outbreak has been traced in China late 2019 and then was transmitted into more than 25 countries. A total of 49 papers have been published in 20 journals during the last January and current February. These papers tried to explain the source of virus, the transmission route, genomic map and the similarity to previous viruses as well as the pathogenesis, symptoms and treatment methods. The huge numbers of the articles which were published on 2019-nCoV make confusing for the readers, since many of the articles are addressed similar topics. In this paper a systematic analysis was conducted for the published articles. The finding of these papers were summarized. Moreover, the present paper aim to highlight the responses of scientists and Journals for the 2019-nCoV outbreak. This paper reviewed 49 peer viewed articles while hundreds article still in the preprint. It was appeared that the Lancet journal has the highest numbers of publications (29%) which given an early alarm for 2019-nCoV. The first paper suggested Baricitinib as potential treatment for 2019-nCoV acute respiratory disease was published on 3 February in the Lancet Journal. In 16 January 2020, the genomic characteristics of the virus was published, followed by several papers on the diagnostic of the virus, pathogenicity and symptoms was more clear on 29 January. The Nature Journal was the fist which given an alarm for the 2019-nCoV outbreak. In conclusion source of 2019-nCoV, treatment methods, as well as vaccines, pathogenicity of the virus in the patient with HIV or other virus infections, transmission to fetus in the pregnant women still need more investigation.

Funding: None.

Declaration of Interest: There is no competing interest among the authors.

Keywords: novel coronavirus (2019-nCoV); sources, transmission route; genomic map; pathogenicity; symptoms; therapeutics

Suggested Citation

Al-Gheethi, Adel and Noman, Efaq and Al-Maqtari, Qais Ali and Hezam, Kamal and Mohamed, Radin and Talip, Balkis and Ismail, Norli, Novel Coronavirus (2019-nCoV) Outbreak; A Systematic Review for Published Papers (2/9/2020). Available at SSRN: https://ssrn.com/abstract=3537085 or http://dx.doi.org/10.2139/ssrn.3537085

Adel Al-Gheethi (Contact Author)

Universiti Tun Hussein Onn Malaysia (UTHM) - Micropollutant Research Centre (MPRC) ( email )

Malaysia

Efaq Noman

Taiz University - Department of Applied Microbiology

Yemen

Qais Ali Al-Maqtari

Jiangnan University - State Key Laboratory of Food Science and Technology

Wuxi
China

Kamal Hezam

Taiz University - Department of Applied Microbiology

Yemen

Radin Mohamed

Universiti Tun Hussein Onn Malaysia (UTHM) - Micropollutant Research Centre (MPRC)

Malaysia

Balkis Talip

Universiti Tun Hussein Onn Malaysia (UTHM) - Faculty of Applied Sciences and Technology

Malaysia

Norli Ismail

Universiti Sains Malaysia (USM) - Environmental Technology Division

Malaysia

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