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The Epidemiological and Clinical Characteristics of 2019 Novel Coronavirus Infection in Changsha, China

14 Pages Posted: 13 Feb 2020

See all articles by Yi Shi Li Liu

Yi Shi Li Liu

Hunan Normal University - Department of Infectious Disease

Dongcui Zhang

Hunan Normal University - Department of Infectious Disease

Shigang Tang

Hunan Normal University - Department of Infectious Disease

Haiou Chen

Hunan Normal University - Department of Infectious Disease

Liang Chen

Hunan Normal University - Department of Infectious Disease

Xinchun He

Hunan Normal University - Department of Infectious Disease

Ming Tong

Hunan Normal University - Department of Infectious Disease

Meng Liu

Hunan Normal University - Department of Infectious Disease

Yihe Lin

Hunan Normal University - Department of Infectious Disease

Baining Zhu

Hunan Normal University - Department of Infectious Disease

Xin Su

Hunan Normal University - Department of Infectious Disease

More...

Abstract

Background: 2019 novel coronavirus infection is high epidemical in China from January 2020. It is very important to detect it rapidly because of its high infectivity. We aimed to know the sensitivity of real-time RT-PCR assay, clarify more about the epidemiological and clinical characteristics of 2019-nCoV infection outside Wuhan.

Method: In this retrospective study,we included all suspected cases in Hunan Provincial people's hospital from 8th January to 8th February 2020. All cases were detected by real-time RT-PCR assay. We analysed the sensitivity of real-time RT-PCR assay, and observed the epidemiological and clinical characteristic of confirmed cases.

Findings: 560 suspected cases with 2019 novel coronavirus infection on Fever outpatient department of Hunan Provincial peoples' hospital, there were 24 confirmed cases. The sensitivity of real-time RT-PCR assay was 100%. 3 confirmed cases were asymptoms type, 3 confirmed cases were light type, most of them were medium type. There is a family cluster phenomenon.

Conclusion: 2019-nCoV infection can present asymptoms type and light type. The real-time RT-PCR assay provide a good method to detect it.

Funding: This paper was supported by Scientific Research Fund from Hunan Provincial Health Committee (NO.20200034).

Declaration of Interest: All authors declare that they have no conflict of interest.

Ethical Approval: All procedures performed in studies involving human participants were in accordance with the ethical standards of the Ethics Committee of the Hunan Provincial people's Hospital and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Keywords: epidemiological and clinical characteristics; 2019-nCov

Suggested Citation

Liu, Yi Shi Li and Zhang, Dongcui and Tang, Shigang and Chen, Haiou and Chen, Liang and He, Xinchun and Tong, Ming and Liu, Meng and Lin, Yihe and Zhu, Baining and Su, Xin, The Epidemiological and Clinical Characteristics of 2019 Novel Coronavirus Infection in Changsha, China (2/10/2020). Available at SSRN: https://ssrn.com/abstract=3537093 or http://dx.doi.org/10.2139/ssrn.3537093

Yi Shi Li Liu (Contact Author)

Hunan Normal University - Department of Infectious Disease ( email )

China

Dongcui Zhang

Hunan Normal University - Department of Infectious Disease

China

Shigang Tang

Hunan Normal University - Department of Infectious Disease

China

Haiou Chen

Hunan Normal University - Department of Infectious Disease

China

Liang Chen

Hunan Normal University - Department of Infectious Disease

China

Xinchun He

Hunan Normal University - Department of Infectious Disease

China

Ming Tong

Hunan Normal University - Department of Infectious Disease

China

Meng Liu

Hunan Normal University - Department of Infectious Disease

China

Yihe Lin

Hunan Normal University - Department of Infectious Disease

China

Baining Zhu

Hunan Normal University - Department of Infectious Disease

China

Xin Su

Hunan Normal University - Department of Infectious Disease

China

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