Preprints with The Lancet is a collaboration between The Lancet Group of journals and SSRN to facilitate the open sharing of preprints for early engagement, community comment, and collaboration. Preprints available here are not Lancet publications or necessarily under review with a Lancet journal. These preprints are early-stage research papers that have not been peer-reviewed. The usual SSRN checks and a Lancet-specific check for appropriateness and transparency have been applied. The findings should not be used for clinical or public health decision-making or presented without highlighting these facts. For more information, please see the FAQs.
2019-nCoV Pneumonia in a Normal Work Infectious Diseases Hospital Besides Hubei Province, China
18 Pages Posted: 25 Feb 2020
More...Abstract
Background: Current outbreak of the new type of novel coronavirus (2019-nCoV) pneumonia in Wuhan, China has drawn attention of the public health system all over the world. This new infectious disease spread extraordinarily in many other areas of China and other countries. Previous investigations reported patients in Wuhan city often progressed into severe or critical and had a higher mortality rate. One of the main reasons was that there are too many patients which far exceeded the admission capacity of the hospital.
Methods: To investigate the characteristics of patients in medical care running normal hospital, which is seldom reported before, we collected the clinical data of 298 patients in our hospital, trying to figure out some clues to manage this disease.
Findings: Our data showed elders and people with underlying diseases are easier to develop to severe or critical situation. Only 192 (64.4%) patients presented fever at onset of illness. Most of the patients 240(80.6%) were non-severe affected individuals, who turned well in the end usually. Other organ injuries including liver, renal, and myocardial were seldom and most occurred at the later stage of the disease. Only a minority of the patients (32, 10.7%) received invasive mechanical ventilation, of which 2 patients received extracorporeal membrane oxygenation. To date, the overall mortality rate of these patients remains 0.
Interpretation: In conclusion, properly running of hospital system may effectively manage the patients of 2019-nCoV pneumonia.
Funding Statement: National Infectious Diseases Clinical Research Center.
Declaration of Interests: All authors declare no competing interests.
Ethics Approval Statement: Data collection and analysis of cases and close contacts were determined by the National Health Commission of the People’s Republic of China to be part of a continuing public health outbreak investigation and were thus considered exempt from institutional review board approval.
Keywords: 2019-nCoV; outbreak; Wuhan
Suggested Citation: Suggested Citation