lancet-header

Preprints with The Lancet is a collaboration between The Lancet Group of journals and SSRN to facilitate the open sharing of preprints for early engagement, community comment, and collaboration. Preprints available here are not Lancet publications or necessarily under review with a Lancet journal. These preprints are early-stage research papers that have not been peer-reviewed. The usual SSRN checks and a Lancet-specific check for appropriateness and transparency have been applied. The findings should not be used for clinical or public health decision-making or presented without highlighting these facts. For more information, please see the FAQs.

2019-nCoV Pneumonia in a Normal Work Infectious Diseases Hospital Besides Hubei Province, China

18 Pages Posted: 25 Feb 2020

See all articles by Cai Qingxian

Cai Qingxian

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

Deliang Huang

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

Pengcheng Ou

Southern University of Science and Technology - Department of Infectious Diseases

Hong Yu

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

Zhibin Zhu

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

Zhang Xia

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

Yinan Su

Southern University of Science and Technology - School of Medicine

Zhenghua Ma

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

Yiming Zhang

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

Zhiwei Li

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

He Qing

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

Yang Fu

Southern University of Science and Technology - School of Medicine

Jun Chen

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

Lei Liu

Southern University of Science and Technology - Pulmonary Diseases Department Two

More...

Abstract

Background: Current outbreak of the new type of novel coronavirus (2019-nCoV) pneumonia in Wuhan, China has drawn attention of the public health system all over the world. This new infectious disease spread extraordinarily in many other areas of China and other countries. Previous investigations reported patients in Wuhan city often progressed into severe or critical and had a higher mortality rate. One of the main reasons was that there are too many patients which far exceeded the admission capacity of the hospital.

Methods: To investigate the characteristics of patients in medical care running normal hospital, which is seldom reported before, we collected the clinical data of 298 patients in our hospital, trying to figure out some clues to manage this disease.

Findings: Our data showed elders and people with underlying diseases are easier to develop to severe or critical situation. Only 192 (64.4%) patients presented fever at onset of illness. Most of the patients 240(80.6%) were non-severe affected individuals, who turned well in the end usually. Other organ injuries including liver, renal, and myocardial were seldom and most occurred at the later stage of the disease. Only a minority of the patients (32, 10.7%) received invasive mechanical ventilation, of which 2 patients received extracorporeal membrane oxygenation. To date, the overall mortality rate of these patients remains 0.

Interpretation: In conclusion, properly running of hospital system may effectively manage the patients of 2019-nCoV pneumonia.

Funding Statement: National Infectious Diseases Clinical Research Center.

Declaration of Interests: All authors declare no competing interests.

Ethics Approval Statement: Data collection and analysis of cases and close contacts were determined by the National Health Commission of the People’s Republic of China to be part of a continuing public health outbreak investigation and were thus considered exempt from institutional review board approval.

Keywords: 2019-nCoV; outbreak; Wuhan

Suggested Citation

Qingxian, Cai and Huang, Deliang and Ou, Pengcheng and Yu, Hong and Zhu, Zhibin and Xia, Zhang and Su, Yinan and Ma, Zhenghua and Zhang, Yiming and Li, Zhiwei and Qing, He and Fu, Yang and Chen, Jun and Liu, Lei, 2019-nCoV Pneumonia in a Normal Work Infectious Diseases Hospital Besides Hubei Province, China (2/12/2020). Available at SSRN: https://ssrn.com/abstract=3542163 or http://dx.doi.org/10.2139/ssrn.3542163

Cai Qingxian

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

China

Deliang Huang

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

China

Pengcheng Ou

Southern University of Science and Technology - Department of Infectious Diseases

Shenzhen, 518020
China

Hong Yu (Contact Author)

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

China

Zhibin Zhu

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

China

Zhang Xia

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

China

Yinan Su

Southern University of Science and Technology - School of Medicine

No 1088, xueyuan Rd.
Xili, Nanshan District
Shenzhen, Guangdong 518055
China

Zhenghua Ma

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

China

Yiming Zhang

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

China

Zhiwei Li

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

China

He Qing

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

China

Yang Fu

Southern University of Science and Technology - School of Medicine

No 1088, xueyuan Rd.
Xili, Nanshan District
Shenzhen, Guangdong 518055
China

Jun Chen

Southern University of Science and Technology - National Clinical Research Center for Infectious Diseases

China

Lei Liu

Southern University of Science and Technology - Pulmonary Diseases Department Two ( email )

Shenzhen
China
+86-13510333313 (Phone)