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Protection of 318 Inflammatory Bowel Disease Patients from the Outbreak and Rapid Spread of COVID-19 Infection in Wuhan, China

20 Pages Posted: 27 Feb 2020

See all articles by Ping An

Ping An

Wuhan University - Department of Gastroenterology

Mengyao Ji

Wuhan University - Key Laboratory of Hubei Province for Digestive System Disease; Wuhan University - Department of Gastroenterology

Haixia Ren

Wuhan University - Department of Gastroenterology

Juan Su

Wuhan University - Department of Gastroenterology

Jian Kang

Wuhan University - Department of Gastroenterology

Anning Yin

Wuhan University - Department of Gastroenterology

Qian Zhou

Wuhan University - Department of Gastroenterology

Linyong Shen

Wuhan University - Department of Gastroenterology

Liang Zhao

Wuhan University - Department of Gastroenterology

Xiaoda Jiang

Wuhan University - Key Laboratory of Hubei Province for Digestive System Disease

Yong Xiao

Wuhan University - Department of Gastroenterology

Wei Tan

Wuhan University - Department of Gastroenterology

Xiaoguang Lv

Wuhan University - Department of Gastroenterology

Jiao Li

Wuhan University - Department of Gastroenterology

Shuzhong Liu

Wuhan University - Department of Gastroenterology

Jing Zhou

Wuhan University - Department of Gastroenterology

Hongbin Chen

Wuhan University - Department of Respiratory Medicine

Yaqing Xu

Wuhan University - Infection Control Department

Jun Liu

Wuhan University - Department of Gastroenterology

Mingkai Chen

Wuhan University - Department of Gastroenterology

Jiwang Cao

Wuhan University - Department of Gastroenterology

Zhongyin Zhou

Wuhan University - Department of Gastroenterology

Lei Shen

Wuhan University - Department of Gastroenterology

Shiyun Tan

Wuhan University - Department of Gastroenterology

Honggang yu

Wuhan University - Department of Gastroenterology

Weiguo Dong

Wuhan University - Department of Gastroenterology

Yijuan Ding

Wuhan University - Department of Gastroenterology; Wuhan University - Department of Gastroenterology

More...

Abstract

Background: An outbreak and worldwide spread of COVID-19 was derived from Wuhan, China where over half of the confirmed COVID-19 cases were reported. Protection for special populations at high infection risk such as patients with inflammatory bowel diseases (IBD) is extremely urgent and challenging.

Methods: We kept alerts since the first reported COVID-19 case and started to send educational and instructional alerts and took measures to 318 registered IBD patients (204 UC and 114 CD) 20 days earlier to the shutdown of Wuhan. The patients’ infection risks, responses to our alerts and actions were assessed and reported diagnosis of COVID-19 infection was recorded.

Findings: With the early and later upgrading alerts and actions for COVID-19 prevention and control, all registry IBD patients received and responsed to our timely guidance. Till now none of them reported COVID-19 infection.

Interpretation: Our early warning and protective actions for prevention are undoubtedly the most critical step during this unpredictable storm. Well consciousness to prevent and control infection, timely and decisive adoption and adjustment of protective measures are the key to protection for our IBD patients. Our experience provides inspirative encouragements and suggestions in current COVID-19 worldwide spread and future pandemic diseases.

Funding Statement: The National Natural Science Foundation of China [Grant Nos. 81870392 to Weiguo Dong]; The National Natural Science Foundation of China [Grant Nos. 81302131 to Ping An]; The National Natural Science Foundation of China [Grant Nos. 81901817 to Mengyao Ji].

Declaration of Interests: All authors declared no conflict of interest.

Ethics Approval Statement: The study protocol was approved by the ethics committee of Renmin Hospital of Wuhan University and waiver of informed consent was obtained.

Keywords: COVID-19, inflammatory bowel disease, Protection

Suggested Citation

An, Ping and Ji, Mengyao and Ren, Haixia and Su, Juan and Kang, Jian and Yin, Anning and Zhou, Qian and Shen, Linyong and Zhao, Liang and Jiang, Xiaoda and Xiao, Yong and Tan, Wei and Lv, Xiaoguang and Li, Jiao and Liu, Shuzhong and Zhou, Jing and Chen, Hongbin and Xu, Yaqing and Liu, Jun and Chen, Mingkai and Cao, Jiwang and Zhou, Zhongyin and Shen, Lei and Tan, Shiyun and yu, Honggang and Dong, Weiguo and Ding, Yijuan, Protection of 318 Inflammatory Bowel Disease Patients from the Outbreak and Rapid Spread of COVID-19 Infection in Wuhan, China (2/20/2020). Available at SSRN: https://ssrn.com/abstract=3543590 or http://dx.doi.org/10.2139/ssrn.3543590

Ping An

Wuhan University - Department of Gastroenterology

China

Mengyao Ji

Wuhan University - Key Laboratory of Hubei Province for Digestive System Disease

China

Wuhan University - Department of Gastroenterology

China

Haixia Ren

Wuhan University - Department of Gastroenterology

China

Juan Su

Wuhan University - Department of Gastroenterology

China

Jian Kang

Wuhan University - Department of Gastroenterology

China

Anning Yin

Wuhan University - Department of Gastroenterology

China

Qian Zhou

Wuhan University - Department of Gastroenterology

China

Linyong Shen

Wuhan University - Department of Gastroenterology

China

Liang Zhao

Wuhan University - Department of Gastroenterology

China

Xiaoda Jiang

Wuhan University - Key Laboratory of Hubei Province for Digestive System Disease

China

Yong Xiao

Wuhan University - Department of Gastroenterology

China

Wei Tan

Wuhan University - Department of Gastroenterology

China

Xiaoguang Lv

Wuhan University - Department of Gastroenterology

China

Jiao Li

Wuhan University - Department of Gastroenterology

China

Shuzhong Liu

Wuhan University - Department of Gastroenterology

China

Jing Zhou

Wuhan University - Department of Gastroenterology

China

Hongbin Chen

Wuhan University - Department of Respiratory Medicine

Wuhan
China

Yaqing Xu

Wuhan University - Infection Control Department

Wuhan
China

Jun Liu

Wuhan University - Department of Gastroenterology

China

Mingkai Chen

Wuhan University - Department of Gastroenterology

China

Jiwang Cao

Wuhan University - Department of Gastroenterology

China

Zhongyin Zhou

Wuhan University - Department of Gastroenterology

China

Lei Shen

Wuhan University - Department of Gastroenterology

China

Shiyun Tan

Wuhan University - Department of Gastroenterology ( email )

China

Honggang Yu

Wuhan University - Department of Gastroenterology ( email )

China

Weiguo Dong

Wuhan University - Department of Gastroenterology ( email )

China

Yijuan Ding (Contact Author)

Wuhan University - Department of Gastroenterology

China

Wuhan University - Department of Gastroenterology

China

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