lancet-header
Preprints with The Lancet is part of SSRN´s First Look, a place where journals and other research experts identify content of interest prior to publication. These preprint papers are not peer-reviewed. Authors have either opted in at submission to The Lancet family of journals to post their preprints on Preprints with The Lancet, or submitted directly via SSRN. The usual SSRN checks and a Lancet-specific check for appropriateness and transparency have been applied. Preprints available here are not Lancet publications or necessarily under review with a Lancet journal. These papers should not be used for clinical decision making or reporting of research to a lay audience without indicating that this is preliminary research that has not been peer-reviewed. For more information see the Comment published in The Lancet, or visit The Lancet´s FAQ page, and for any feedback please contact preprints@lancet.com

Epidemiological and Clinical Characteristics of 944 Cases of 2019 Novel Coronavirus Infection of Non-COVID-19 Exporting City, Zhejiang, China

22 Pages Posted: 28 Feb 2020

See all articles by Yani Kuang

Yani Kuang

Wenzhou Medical University - Affiliated Taizhou Hospital

Huangqi Zhang

Wenzhou Medical University - Affiliated Taizhou Hospital

Rongzhen Zhou

Wenzhou Medical University - Affiliated Taizhou Hospital

Shuangxiang Lin

Wenzhou Medical University - Affiliated Taizhou Hospital

Minjie Lin

Wenzhou Medical University - Affiliated Taizhou Hospital

Jian Wang

Wenzhou Medical University - Affiliated Taizhou Hospital

Peipei Pang

GE HealthCare China

Ling Ma

BMC, United-Imaging

Wenbin Ji

Wenzhou Medical University - Affiliated Taizhou Hospital

More...

Abstract

Background: Since December 8, 2019, China is experiencing an outbreak of pneumonia caused by 2019 novel coronavirus (COVID-19). The purpose of this study is to get a better understanding of the epidemiology and clinical characteristics of the disease in non-COVID-19-exporting city, Zhejiang.

Methods: In this study, we collected the information of all confirmed cases of COVID-19 in Zhejiang province from Jan 1 to Feb 10, 2020. We analyzed the epidemiological characteristics and clinical characteristics by statistical methods, and the correlation between the clinical factors and COVID-19 infection was compared and analyzed.

Findings: Of the 944 COVID-19 infected patients, 834 (89.2%) had contact with people from Hubei province or confirmed patients. The mean age of the patients was 49.5 years (SD15.8), including 480 males and 483 females. A total of 918 patients (97.2%) presented with different clinical manifestations and 26 (3.2%) had no clinical manifestations. They had clinical manifestations of fever (584 [61.9%]patients), cough (311 [32.9%]patients), weak (93[9.9%]patients), runny (21[2.7%]patients), sore throat (64[6.8%]patients), diarrhea (21[2.7%]patients), headache or dizziness (79[10.1%]patients), muscle ache (45 [5.8%]patients), chest tightness (19 [2.4%]patients).The average temperature of the patients with fever was 37.9 (SD0.5).In addition, 167 cases (74.6%) showed pulmonary CT changes, and 11 cases (4.9%) showed no pulmonary CT changes. From Jan 21 to Jan 29, 2020, the number of cases increased dramatically, and it is now in a downward trend.

Interpretation: The age of the susceptible population in Zhejiang province is consistent with that of whole China. The CT positive rate in Zhejiang province is higher than that in Wuhan. Compared with Wuhan, Zhejiang province has seen more asymptomatic infections, and fever and cough are more common in Zhejiang province. During the period of disease prevention and control, great attention should be paid to the cities with non-exporting cases.

Funding Statement: The authors stated: "None."

Declaration of Interests: The authors declare no competing interests.

Keywords: COVID-19; COVID-19 pneumonia; epidemiology; clinical characteristics

Suggested Citation

Kuang, Yani and Zhang, Huangqi and Zhou, Rongzhen and Lin, Shuangxiang and Lin, Minjie and Wang, Jian and Pang, Peipei and Ma, Ling and Ji, Wenbin, Epidemiological and Clinical Characteristics of 944 Cases of 2019 Novel Coronavirus Infection of Non-COVID-19 Exporting City, Zhejiang, China (February 20, 2020). Available at SSRN: https://ssrn.com/abstract=3543604 or http://dx.doi.org/10.2139/ssrn.3543604

Yani Kuang

Wenzhou Medical University - Affiliated Taizhou Hospital

Taizhou
China

Huangqi Zhang

Wenzhou Medical University - Affiliated Taizhou Hospital

Taizhou
China

Rongzhen Zhou

Wenzhou Medical University - Affiliated Taizhou Hospital

Taizhou
China

Shuangxiang Lin

Wenzhou Medical University - Affiliated Taizhou Hospital

Taizhou
China

Minjie Lin

Wenzhou Medical University - Affiliated Taizhou Hospital

Taizhou
China

Jian Wang

Wenzhou Medical University - Affiliated Taizhou Hospital

Taizhou
China

Peipei Pang

GE HealthCare China

China

Ling Ma

BMC, United-Imaging

Wuhan
China

Wenbin Ji (Contact Author)

Wenzhou Medical University - Affiliated Taizhou Hospital ( email )

Taizhou
China

Click here to go to TheLancet.com

Paper statistics

Abstract Views
1,591
Downloads
254
PlumX Metrics