lancet-header
Preprints with The Lancet is part of SSRN´s First Look, a place where journals and other research experts identify content of interest prior to publication. These preprint papers are not peer-reviewed and are posted here as part of a 12-month trial. Authors have either opted in at submission to The Lancet family of journals to post their preprints on Preprints with The Lancet, or submitted directly via SSRN. The usual SSRN checks and a Lancet-specific check for appropriateness and transparency have been applied. These papers should not be used for clinical decision making or reporting of research to a lay audience without indicating that this is preliminary research that has not been peer-reviewed. For more information see the Comment published in The Lancet, or visit The Lancet´s FAQ page, and for any feedback please contact preprints@lancet.com

Evaluation of the Clinical Characteristics of Suspected or Confirmed Cases of COVID-19 During Home Care with Isolation: A New Retrospective Analysis Based on O2O

24 Pages Posted: 6 Mar 2020

See all articles by Hui Xu

Hui Xu

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Anesthesiology

Sufang Huang

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Emergency Medicine

Shangkun Liu

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Anesthesiology

Juan Deng

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Emergency Medicine

Bo Jiao

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Anesthesiology

Ling Ai

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Anesthesiology

Yaru Xiao

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Emergency Medicine

Li Yan

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Emergency Medicine

Shusheng Li

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Emergency Medicine

More...

Abstract

Background: The recent outbreak of the novel coronavirus in December 2019 (COVID-19) has activated top-level response nationwide. We developed a new treatment model based on the online-to-offline (O2O) model for the home isolated patients, because in the early stages the medical staff were insufficient to cope with so many patients.

Methods: In this single-centered, retrospective study, we enrolled 48 confirmed/suspected COVID-19 patients who underwent home isolation in Wuhan between January 6 and January 31, 2020. By WeChat and online document editing all patients were treated with medical observation scale. The clinical indications such as Fever, Muscle soreness, Dyspnea and Lack of strength were collected with this system led by medical staff in management, medicine, nursing, rehabilitation and psychology.

Findings: The mean age of 48 patients was 39·08±13·88 years, 35(72·9%) were women. Compared with non-hospitalized patients, inpatients were older(≥70years, 2·4% vs 33·3%, P<0·04). All inpatients had fever, 50% inpatients had coughs and showed infiltration in both lungs at the time of diagnosis. 33·3% inpatients exhibited negative changes in their CT results at initial diagnosis. The body temperature of non-hospitalized patients with mild symptoms returned to normal by day 4-5. While dyspnea peaked on day 6 for non-hospitalized patients with mild symptoms, it persisted in hospitalized patients and exacerbated over time. The lack of strength and muscle soreness were both back to normal by day 4 for non-hospitalized patients.

Interpretation: Monitoring the trends of symptoms is more important for identifying severe cases. Excessive laboratory data and physical examination are not necessary for the evaluation of patients with mild symptoms. The system we developed is the first to convert the subjective symptoms of patients into objective scores. This type of O2O, subjective-to-objective strategy may be used in regions with similar highly infectious diseases to minimize the possibility of infection among medical staff.

Funding Statement: The authors stated "no funding."

Declaration of Interests: The authors declare no competing interests.

Ethics Approval Statement: The study was approved by Tongji Hospital Ethics Committee before data were collected retrospectively.

Keywords: COVID-19; home care with isolation; online-to-offline model; medical observation scales

Suggested Citation

Xu, Hui and Huang, Sufang and Liu, Shangkun and Deng, Juan and Jiao, Bo and Ai, Ling and Xiao, Yaru and Yan, Li and Li, Shusheng, Evaluation of the Clinical Characteristics of Suspected or Confirmed Cases of COVID-19 During Home Care with Isolation: A New Retrospective Analysis Based on O2O (2/29/2020). Available at SSRN: https://ssrn.com/abstract=3548746 or http://dx.doi.org/10.2139/ssrn.3548746

Hui Xu

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Anesthesiology

Wuhan
China

Sufang Huang

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Emergency Medicine

Wuhan
China

Shangkun Liu

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Anesthesiology

Wuhan
China

Juan Deng

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Emergency Medicine

Wuhan
China

Bo Jiao

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Anesthesiology

Wuhan
China

Ling Ai

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Anesthesiology

Wuhan
China

Yaru Xiao

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Emergency Medicine

Wuhan
China

Li Yan (Contact Author)

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Emergency Medicine ( email )

Wuhan
China

Shusheng Li

Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Emergency Medicine

Wuhan
China

Click here to go to TheLancet.com

Paper statistics

Abstract Views
517
Downloads
94