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Epidemiological Features of Coronavirus Disease 2019 (COVID-19) in a Province Outside of Wuhan

19 Pages Posted: 24 Mar 2020

See all articles by Lei Shi

Lei Shi

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Qian Li

Xi’an CDC

Kang Li

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Jie Zheng

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Yingli He

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Xi Zhang

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Xianfeng Gong

Xi'an Chest Hospital

Wei Wang

Ankang Central Hospital

Qing Zhang

Hanzhong Central Hospital

Chao Dai

Hanzhong Central Hospital

Wenxuan Zhao

The Second People's Hospital of Hanzhong

Xuefei Meng

Weinan Central Hospital

Feng Du

Baoji Central Hospital

Pei Fan

Tongchuan People’s Hospital

Chunyan Li

The Second People's Hospital of Yanan

Chunyan Gao

Shangluo Central Hospital

Yuan Yang

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Xiaojing Liu

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Yunru Chen

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Jinfeng Liu

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Jianzhou Li

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Nan Yang

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Yinghua Niu

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Hongmei Chen

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Guoyu Zhang

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Taotao Yan

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Li Zhu

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Qunying Han

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Wanhu Fan

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital; Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Feng Ye

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Shumei Lin

Xi'an Jiaotong University (XJTU)

Zhengwen Liu

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Yingren Zhao

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

Tianyan Chen

Xi'an Jiaotong University (XJTU) - Department of Infectious Diseases

More...

Abstract

Background: A pneumonia associated with 2019 novel coronavirus (2019-nCoV, subsequently named SARS-CoV2) emerged in Wuhan, China from December, 2019. Wuhan has been closed since January 23, 2020, and other regions have taken strict control measures. We aimed to describe the epidemiological characteristics of 2019 coronavirus disease (COVID-19) in a province outside of Wuhan.

Methods: We prospectively included all 245 confirmed cases of COVID-19 in Shaanxi province from Jan 23 to Feb 22, 2020. Cases were confirmed by real-time RT-PCR and were analyzed for epidemiological. Data were obtained from Health Commission of Shaanxi Province.

Findings: 1. Among the 245 patients, 132 (53.9%) were males and 113 (46.1%) were females. The average age was 46.15±16.43 years, ranging from 3 to 89 years. 2. For the clinical type, 84.90% (208/245) patients were moderate type, and only 0.41% (1/245) was asymptomatic. 3. Of the 245 patients, 116 (47.35%) were imported case, 114 (46.53%) were non-imported case, and 15 (6.12%) were unknow exposure. 4. 48.57% (119/245) cases were family cluster, involving 42 families. The most common patterns of COVID-19 family cluster was between husband and wife or between parents and children.

Interpretation: Of the patients we observed, all the population was susceptible to COVID-19. Most cases were moderate type, and only 0.41% was asymptomatic. The COVID-19 infection was of family clustering onset outside of Wuhan, which indicates the suspected or mild patients may have the risk of spreading disease if they stay at home.

Funding Statement: This study was funded by the Key R & D plan of Shaanxi Province (number 2020ZDXM-SF-004).

Declaration of Interests: All authors declare no competing interests.

Ethics Approval Statement: This study belongs to the data analysis of information related to outbreak treatment, which was reviewed and approved by the ethics review committee of Shaanxi Health Commission, with a waiver of informed consent.

Keywords: COVID-19, Epidemiological features, family cluster

Suggested Citation

Shi, Lei and Li, Qian and Li, Kang and Zheng, Jie and He, Yingli and Zhang, Xi and Gong, Xianfeng and Wang, Wei and Zhang, Qing and Dai, Chao and Zhao, Wenxuan and Meng, Xuefei and Du, Feng and Fan, Pei and Li, Chunyan and Gao, Chunyan and Yang, Yuan and Liu, Xiaojing and Chen, Yunru and Liu, Jinfeng and Li, Jianzhou and Yang, Nan and Niu, Yinghua and Chen, Hongmei and Zhang, Guoyu and Yan, Taotao and Zhu, Li and Han, Qunying and Fan, Wanhu and Ye, Feng and Lin, Shumei and Liu, Zhengwen and Zhao, Yingren and Chen, Tianyan, Epidemiological Features of Coronavirus Disease 2019 (COVID-19) in a Province Outside of Wuhan (3/9/2020). Available at SSRN: https://ssrn.com/abstract=3552842 or http://dx.doi.org/10.2139/ssrn.3552842

Lei Shi

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Qian Li

Xi’an CDC

Shaanxi, 710000
China

Kang Li

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Jie Zheng

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Yingli He

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Xi Zhang

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Xianfeng Gong

Xi'an Chest Hospital

Shaanxi, 710100
China

Wei Wang

Ankang Central Hospital

Ankang
China

Qing Zhang

Hanzhong Central Hospital

Hanzhong
China

Chao Dai

Hanzhong Central Hospital

Hanzhong
China

Wenxuan Zhao

The Second People's Hospital of Hanzhong

Shaanxi, 723000
China

Xuefei Meng

Weinan Central Hospital

Weinan
China

Feng Du

Baoji Central Hospital

8 Jiangtan Road
Baoji, 721008
China

Pei Fan

Tongchuan People’s Hospital

Tongchuan
China

Chunyan Li

The Second People's Hospital of Yanan

Shaanxi, 716004
China

Chunyan Gao

Shangluo Central Hospital

Shangluo
China

Yuan Yang

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Xiaojing Liu

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Yunru Chen

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Jinfeng Liu

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Jianzhou Li

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Nan Yang

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Yinghua Niu

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Hongmei Chen

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Guoyu Zhang

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Taotao Yan

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Li Zhu

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Qunying Han

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Wanhu Fan

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Feng Ye

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Shumei Lin

Xi'an Jiaotong University (XJTU)

26 Xianning W Rd.
Xi'an Jiao Tong University
Xi'an, Shaanxi 710049
China

Zhengwen Liu

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Yingren Zhao

Xi'an Jiaotong University (XJTU) - First Affiliated Hospital

26 Xianning W Rd.
Xi'an, Shaanxi 710049
China

Tianyan Chen (Contact Author)

Xi'an Jiaotong University (XJTU) - Department of Infectious Diseases ( email )

China

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