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Clinical Characteristics of 545 Cases Confirmed COVID-19 in Wuhan Stadium Cabin Hospital

17 Pages Posted: 24 Mar 2020

See all articles by Lei Shu

Lei Shu

Nanjing Medical University - Department of Respiratory Medicine

Xiaoyan Wang

Nanjing Medical University - Department of Geriatric Cardiology; Nanjing Medical University - Department of Geriatric Cardiology

Mingquan Li

Nanjing University - Department of Neurology

Xiaolin Chen

Nanjing Medical University - Department of Respiratory Medicine

Lei Shi

Nanjing Medical University - Department of Respiratory Medicine; Nanjing Medical University - Department of Respiratory Medicine

Mingjing Wu

Nanjing Medical University - Department of Respiratory Medicine; Nanjing Medical University - Department of Respiratory Medicine

Kaili Deng

Nanjing Medical University - Department of Respiratory Medicine; Nanjing Medical University - Department of Respiratory Medicine

Jing Wei

Nanjing Medical University - Department of Respiratory Medicine

Xueli Wang

Nanjing Medical University - Department of Respiratory Medicine

Yang Cao

Nanjing Medical University - Department of Respiratory Medicine

Jiaxin Yan

Nanjing Medical University - Department of Respiratory Medicine

Ganzhu Feng

Nanjing Medical University - Department of Respiratory Medicine

More...

Abstract

Background: In order to report the clinical characteristics of COVID-19 Patients in Wuhan Stadium Cabin Hospital in Hubei Province.

Methods: A total of 545 patients with mild and moderate types of coronavirus pneumonia (COVID-19) treated in the Wuhan Stadium Cabin Hospital were selected from Feb 13 to Feb 29, 2020, and their general information, epidemiological history, incidence, clinical manifestations, laboratory tests, and imaging data, treatment and prognosis were collected for analysis.

Finding: The total 545 patients were from 11 to 78 years old, with a median age of 50 years, 264 males (48.44%) and 281 females (51.56%), there were 423 cases (77.61%) with no smoking history, 122 cases (22.39%) with a history of smoking. The main clinical symptoms were fever and cough, which accounted for 284 (51.92%) and 382 cases (70.09%), the other symptoms included 77 cases (14.77%) of fatigue and muscle aches, 89 cases (16.27%) of dyspnea, 95 cases (17.37%) of chest tightness, 52 cases (9.51%) of headache, diarrhea was uncommon, only 49 cases (8.96%). On admission, ground-glass opacity was the most common radiologic finding from chest computed tomography (CT) scanning (50.64%), 108 cases (19.82%) had no abnormal density shadow, 29 cases (5.32%) had consolidation, 87 cases (15.96%) had nodular lesion, and 45 cases (8.25%) had interstitial abnormalities. Lymphocytopenia was present in 403 cases (73.94%) of the patients on admission, and C-reactive protein had a slight elevated in 543 cases (99.63%). Up to now, 468 cases (85.77%) were discharged from the hospital, and no patient died, the average hospital stay for discharge patients was 15 days.

Interpretation: Covid-19 is a highly infectious disease, and mostly are middle-aged and elderly cases, there is no significant difference between males and females. Fever, cough, and fatigue are most the clinical manifestations. Blood tests suggest that white blood cells are most normal and lymphocytes are reduced, C-reactive protein is slightly elevated, and imaging findings are of guiding significance for diagnosis of the disease and therapeutic effect.  At the same time of antiviral treatment, pay attention to nutritional support and gastrointestinal function protection, combined with traditional Chinese medicine treatment is very important. Early diagnosis, isolation, and treatment are essential and critical to control the disease. Cabin hospital, as a fast and effective method for centralized isolation and treatment of patients with infectious diseases, can provide a valuable experience in dealing with public emergency incident.

Funding Statement: None.

Declaration of Interests: Lei Shu, Xiaoyan Wang, Xiaolin Chen, Mingquan Li, Lei Shi, Mingjing Wu, Kaili Deng, Jing Wei, Xueli Wang, Yang Cao, Jiaxin Yan, Ganzhu Feng declared that there were no competing interests.

Ethics Approval Statement: The study was approved by the Ethics Committee of Wuhan Stadium Cabin Hospital, and the written informed consent was waived because of the retrospective nature of the study and belongs to emergency medical service.

Keywords: Coronavirus disease-19 (COVID-19); clinical characteristics; coronavirus pneumonia

Suggested Citation

Shu, Lei and Wang, Xiaoyan and Li, Mingquan and Chen, Xiaolin and Shi, Lei and Wu, Mingjing and Deng, Kaili and Wei, Jing and Wang, Xueli and Cao, Yang and Yan, Jiaxin and Feng, Ganzhu, Clinical Characteristics of 545 Cases Confirmed COVID-19 in Wuhan Stadium Cabin Hospital (3/9/2020). Available at SSRN: https://ssrn.com/abstract=3552844 or http://dx.doi.org/10.2139/ssrn.3552844

Lei Shu (Contact Author)

Nanjing Medical University - Department of Respiratory Medicine ( email )

Nanjing, Jiangsu 211166
China

Xiaoyan Wang

Nanjing Medical University - Department of Geriatric Cardiology

Nanjing, Jiangsu 210029
China

Nanjing Medical University - Department of Geriatric Cardiology

Nanjing, Jiangsu 210029
China

Mingquan Li

Nanjing University - Department of Neurology

Nanjing, Jiangsu 210000
China

Xiaolin Chen

Nanjing Medical University - Department of Respiratory Medicine

Nanjing, Jiangsu 211166
China

Lei Shi

Nanjing Medical University - Department of Respiratory Medicine

Nanjing, Jiangsu 211166
China

Nanjing Medical University - Department of Respiratory Medicine

Nanjing, Jiangsu 211166
China

Mingjing Wu

Nanjing Medical University - Department of Respiratory Medicine

Nanjing, Jiangsu 211166
China

Nanjing Medical University - Department of Respiratory Medicine

Nanjing, Jiangsu 211166
China

Kaili Deng

Nanjing Medical University - Department of Respiratory Medicine

Nanjing, Jiangsu 211166
China

Nanjing Medical University - Department of Respiratory Medicine

Nanjing, Jiangsu 211166
China

Jing Wei

Nanjing Medical University - Department of Respiratory Medicine

Nanjing, Jiangsu 211166
China

Xueli Wang

Nanjing Medical University - Department of Respiratory Medicine

Nanjing, Jiangsu 211166
China

Yang Cao

Nanjing Medical University - Department of Respiratory Medicine

Nanjing, Jiangsu 211166
China

Jiaxin Yan

Nanjing Medical University - Department of Respiratory Medicine

Nanjing, Jiangsu 211166
China

Ganzhu Feng

Nanjing Medical University - Department of Respiratory Medicine ( email )

Nanjing, Jiangsu 211166
China

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