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Clinical Characteristics of 85 Patients Infected by SARS-CoV-2 in Guangxi, China

24 Pages Posted: 1 Apr 2020

See all articles by Wan Chen

Wan Chen

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Emergency

Chunxia Chen

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Research Center of Medical Sciences

Luying Huang

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Respiratory Diseases

Ku Ye

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Nephrology

Liwen Lv

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Emergency

Zhiqiang Qin

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Respiratory Diseases

Hang Liu

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Respiratory Diseases

Bin Xiong

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Intensive Care Unit

Zhihuang Nong

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Pharmacy

Qinwei Ji

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Cardiology

Fan Xu

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Ophthalmology

Xin Xiao

People’s Hospital of Guangxi Zhuang Autonomous Region - Visual Science and Optometry Center

Guo Zhang

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Gastroenterology

Min Li

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Ophthalmology

Jianrong Yang

People’s Hospital of Guangxi Zhuang Autonomous Region - Extracorporeal Department of Hepatobiliary Glands

More...

Abstract

Background: Starting in December 2019, the SARS-CoV-2 virus caused severe pneumonia in Wuhan and spread nationwide and globally. Here, we report the clinical features of COVID-19 patients in Guangxi, China.

Methods: Data of 85 confirmed SARS-CoV-2 infected patients were collected from a designated hospital of Guangxi from Jan 15 to Mar 7, 2020. The epidemiology, baseline, clinical characteristics, laboratory test, treatment and outcome of these patients were analyzed.

Findings: Most of the patients are female (60%). The incidence of local patients in Guangxi is mainly familial clustering. The first symptoms were fever (64.7%) and cough (43.5%). Lymphocytes increased in 45.5% juveniles and lymphocytes decreased in 55.6% severe patients. The infection indexes were not elevated in all juveniles. D-dimer increased (100%) and oxygenation index decreased (44.4%) were observed in the severe group. After two consecutive times of nucleic acid detecting with negative, 3.6% patients showed the phenomenon of recovery of positive. 18 (24%) patients showed linear in chest CT, including 1(10%) juvenile, 1 (11.1%) mild, 14 (29.8%) moderate and 2 (22.2%) severe. All patients received antiviral treatment. 12.9% patients received oxygen through nasal catheters, while 1.2% patients received invasive mechanical ventilation with ECMO. 70.6% patients had been discharged, and 1.2% had died.

Interpretation: COVID-19 patients in Guangxi mainly presented as family clustering. Pulmonary fibrosis occurred in some patients. The number of viral nucleic acid tests in different samples of the body and the chest imaging characteristics of more patients should be further explored.

Funding Statement: This study was supported by the National Natural Science Foundation of China (81701089 and 81960246).

Declaration of Interests: The authors declare no competing interests.

Ethics Approval Statement: The study was approved by ethics committee of the People's Hospital of Guangxi Zhuang Autonomous Region, China. We obtained written consent from the patients.

Keywords: clinical characteristics; SARS-CoV-2; COVID-19; Guangxi; juvenile; severe

Suggested Citation

Chen, Wan and Chen, Chunxia and Huang, Luying and Ye, Ku and Lv, Liwen and Qin, Zhiqiang and Liu, Hang and Xiong, Bin and Nong, Zhihuang and Ji, Qinwei and Xu, Fan and Xiao, Xin and Zhang, Guo and Li, Min and Yang, Jianrong, Clinical Characteristics of 85 Patients Infected by SARS-CoV-2 in Guangxi, China (3/18/2020). Available at SSRN: https://ssrn.com/abstract=3559599 or http://dx.doi.org/10.2139/ssrn.3559599

Wan Chen

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Emergency

Nanning, Guangxi 530021
China

Chunxia Chen

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Research Center of Medical Sciences

Nanning, Guangxi 530021
United States

Luying Huang

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Respiratory Diseases

Nanning, Guangxi 530021
China

Ku Ye

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Nephrology

Nanning, Guangxi 530021
China

Liwen Lv

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Emergency

Nanning, Guangxi 530021
China

Zhiqiang Qin

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Respiratory Diseases

Nanning, Guangxi 530021
China

Hang Liu

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Respiratory Diseases

Nanning, Guangxi 530021
China

Bin Xiong

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Intensive Care Unit

Nanning, Guangxi 530021
China

Zhihuang Nong

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Pharmacy

Nanning, Guangxi 530021
United States

Qinwei Ji

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Cardiology

Nanning
China

Fan Xu

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Ophthalmology

Nanning, Guangxi 530021
China

Xin Xiao

People’s Hospital of Guangxi Zhuang Autonomous Region - Visual Science and Optometry Center

Nanning, Guangxi 530021
China

Guo Zhang

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Gastroenterology ( email )

Nanning, Guangxi 530021
China

Min Li

People’s Hospital of Guangxi Zhuang Autonomous Region - Department of Ophthalmology ( email )

Nanning, Guangxi 530021
China

Jianrong Yang (Contact Author)

People’s Hospital of Guangxi Zhuang Autonomous Region - Extracorporeal Department of Hepatobiliary Glands ( email )

Nanning, Guangxi 530021
China

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