Case Report: Recovery of One ICU-Acquired COVID-19 Patient Via Ozonated Autohemotherapy

15 Pages Posted: 8 Apr 2020

See all articles by Junping Wu

Junping Wu

Tianjin Haihe Hospital

Cherie Tan

Tianjin University - Medical College

Hongzhi Yu

Tianjin Haihe Hospital

Youwei Wang

Tianjin University - Medical College

Yutao Tian

Tianjin University - Medical College

Wenwei Shao

Tianjin University - Medical College

Yifei Zhang

Tianjin University - Medical College

Kuo Zhang

Tianjin University - Medical College

Hongxia Shao

Tianjin Haihe Hospital

Guangjian Ni

Tianjin University - Medical College; Tianjin University

Jun Shen

Tianjin Haihe Hospital

Qi Wu

Tianjin Haihe Hospital

Dong Ming

Tianjin University - Medical College

Date Written: March 26, 2020

Abstract

The rapid spread of COVID-19 results in a pandemic throughout the world, however, there are currently no specific treatments available. We report the first case of ozonated autohemotherapy for a critically ill patient with COVID-19. The patient was diagnosed with severe acute respiratory distress syndrome (ARDS) and life-threatening refractory hypoxemia within 72 hours of the intensive-care unit (ICU) admission. To improve the oxygen delivery, the ozonated autohemotherapy was performed with 40 µg/ml of ozone in 100 ml of blood for 5 days on this patient, who then recovered from ARDS uneventfully and discharged from hospital after viral clearance. This case suggests ozonated autohemotherapy might be an alternative non-invasive medical treatment for critically ill COVID-19 patients.

Note: Funding: Supported by the National Natural Science Foundation and the Tianjin University COVID-19 Contingency fund.

Conflict of Interest: None declared.

Ethical Approval: This clinical protocol was approved as a complementary therapy by the institutional review board of Tianjin University Haihe Hospital on February 16, 2020, while the patient would continue to be treated with allopathic medicine. The patient was an adult recruited from COVID-19 specified ICU at Haihe hospital, and signed an informed consent about medical ozonated autohemotherapy on February 20, 2020.

Suggested Citation

Wu, Junping and Tan, Cherie and Yu, Hongzhi and Wang, Youwei and Tian, Yutao and Shao, Wenwei and Zhang, Yifei and Zhang, Kuo and Shao, Hongxia and Ni, Guangjian and Shen, Jun and Wu, Qi and Ming, Dong, Case Report: Recovery of One ICU-Acquired COVID-19 Patient Via Ozonated Autohemotherapy (March 26, 2020). Available at SSRN: https://ssrn.com/abstract=3561379 or http://dx.doi.org/10.2139/ssrn.3561379

Junping Wu

Tianjin Haihe Hospital ( email )

China

Cherie Tan

Tianjin University - Medical College ( email )

92, Weijin Road
Nankai District
Tianjin, Tianjin 300072
China

Hongzhi Yu

Tianjin Haihe Hospital ( email )

China

Youwei Wang

Tianjin University - Medical College ( email )

92, Weijin Road
Nankai District
Tianjin, Tianjin 300072
China

Yutao Tian

Tianjin University - Medical College ( email )

92, Weijin Road
Nankai District
Tianjin, Tianjin 300072
China

Wenwei Shao

Tianjin University - Medical College ( email )

92, Weijin Road
Nankai District
Tianjin, Tianjin 300072
China

Yifei Zhang

Tianjin University - Medical College ( email )

92, Weijin Road
Nankai District
Tianjin, Tianjin 300072
China

Kuo Zhang

Tianjin University - Medical College ( email )

92, Weijin Road
Nankai District
Tianjin, Tianjin 300072
China

Hongxia Shao

Tianjin Haihe Hospital ( email )

China

Guangjian Ni (Contact Author)

Tianjin University - Medical College ( email )

92, Weijin Road
Nankai District
Tianjin, Tianjin 300072
China

Tianjin University ( email )

92 Weijin Road, Nankai District
Tianjin, Tianjin 300072
China

Jun Shen

Tianjin Haihe Hospital ( email )

China

Qi Wu

Tianjin Haihe Hospital ( email )

China

Dong Ming

Tianjin University - Medical College ( email )

92, Weijin Road
Nankai District
Tianjin, Tianjin 300072
China

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