Does Scorpion Bite Lead to Development of Resistance to the Effect of Local Anaesthetics?

Panditrao MM, Panditrao MM, Khan MI, Yadav N. Does Scorpion Bite Lead to Development of Resistance to the Effect of Local Anaesthetics? Indian J Anaesth 2012; 56:575-8.

5 Pages Posted: 28 May 2020

See all articles by Mridul Panditrao

Mridul Panditrao

Mridul Madhav Panditrao

Padmashree Dr. Vithalrao Vikhe Patil Foundation’s Medical College and Hospital - Department of Anaesthesiology and Intensive Care

Mohd. Irfan Khan

Padmashree Dr. Vithalrao Vikhe Patil Foundation’s Medical College and Hospital - Department of Anaesthesiology and Critical Care

Nikhil Yadav

Padmashree Dr. Vithalrao Vikhe Patil Foundation’s Medical College and Hospital - Department of Anaesthesiology and Critical Care

Date Written: August 24, 2012

Abstract

A patient posted for vaginal hysterectomy was administered subarachnoid block, which failed, so was repeated in one space above. The block failed again, after waiting for 30 min. Patient gave a history of scorpion bite twice, once at the age of 17 years on her right foot and again about 8 months back. Thereafter, balanced general anaesthesia was given. On eighth post-operative day, after explaining about her possible special condition (?Resistance to local anaesthetic agents), the patient was given left median, ulnar and radial nerve blocks at the wrist and local infiltration near the anatomical snuff box. There was neither sensory nor motor block. The scorpion venom is known to affect the pumping mechanism of sodium channels in the nerve fibres, which are involved in the mechanism of action of local anaesthetic drugs, it may be responsible for the development of ‘resistance’ to the action of local anaesthetic agents.

Keywords: resistance to local anaesthetics, scorpion bite, various routes

Suggested Citation

Panditrao, Mridul and Panditrao, Mridul Madhav and Khan, Mohd. Irfan and Yadav, Nikhil, Does Scorpion Bite Lead to Development of Resistance to the Effect of Local Anaesthetics? (August 24, 2012). Panditrao MM, Panditrao MM, Khan MI, Yadav N. Does Scorpion Bite Lead to Development of Resistance to the Effect of Local Anaesthetics? Indian J Anaesth 2012; 56:575-8., Available at SSRN: https://ssrn.com/abstract=3609202

Mridul Madhav Panditrao

Padmashree Dr. Vithalrao Vikhe Patil Foundation’s Medical College and Hospital - Department of Anaesthesiology and Intensive Care ( email )

India

Mohd. Irfan Khan

Padmashree Dr. Vithalrao Vikhe Patil Foundation’s Medical College and Hospital - Department of Anaesthesiology and Critical Care

India

Nikhil Yadav

Padmashree Dr. Vithalrao Vikhe Patil Foundation’s Medical College and Hospital - Department of Anaesthesiology and Critical Care

India

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