A 78-Year Old Urothelial Cancer Patient with Faster Recovery from COVID-19: Potential Benefit from Adjuvant Active Immunotherapy

21 Pages Posted: 4 Jun 2020

See all articles by Jeany Delafiori

Jeany Delafiori

Universidade Estadual de Campinas (UNICAMP) - Innovare Biomarkers Laboratory

João Carlos Cardoso Alonso

Universidade Estadual de Campinas (UNICAMP)

Luiz Augusto dos Santos

Paulínia Municipal Hospital

Diogo Noin de Oliveira

Universidade Estadual de Campinas (UNICAMP) - Innovare Biomarkers Laboratory

Luiz Cláudio Navarro

Universidade Estadual de Campinas (UNICAMP)

Estela Natacha Brandt Busanello

Universidade Estadual de Campinas (UNICAMP) - Innovare Biomarkers Laboratory

Geovana Manzan Sales

Universidade Estadual de Campinas (UNICAMP) - Innovare Biomarkers Laboratory

Arthur Noin de Oliveira

Universidade Estadual de Campinas (UNICAMP) - Innovare Biomarkers Laboratory

Anderson Rezende Rocha

Universidade Estadual de Campinas (UNICAMP)

Nelson Durán

Universidade Estadual de Campinas (UNICAMP) - Instituto de Quimica

Rodrigo Ramos Catharino

Universidade Estadual de Campinas (UNICAMP) - Innovare Biomarkers Laboratory

Wagner Favaro

Universidade Estadual de Campinas (UNICAMP)

Date Written: May 24, 2020

Abstract

A 78-year old male patient under active immunotherapy for high-grade non-muscle invasive bladder cancer presented severe COVID-19. A shorter hospitalization period was observed, leading to the hypothesis of active immunotherapy (OncoTherad) crucial role in association to antiviral and anti-inflammatory treatment in preventing the evolution of pulmonary symptoms to a poor prognosis.

Note: Funding: This work was supported by São Paulo Research Foundation (FAPESP) [2019/05718-3 to J.D. and 2018/10052-1 to W.J.F].

Conflict of Interest: The authors declare no competing interests.

Ethical Approval: This study was approved by the ethics committee at UNICAMP.

Keywords: COVID-19, SARS-CoV-2, Immunotherapy, OncoTherad, Metabolomics

JEL Classification: I1

Suggested Citation

Delafiori, Jeany and Alonso, João Carlos Cardoso and Santos, Luiz Augusto dos and Oliveira, Diogo Noin de and Navarro, Luiz Cláudio and Busanello, Estela Natacha Brandt and Sales, Geovana Manzan and Oliveira, Arthur Noin de and Rocha, Anderson Rezende and Durán, Nelson and Catharino, Rodrigo Ramos and Favaro, Wagner, A 78-Year Old Urothelial Cancer Patient with Faster Recovery from COVID-19: Potential Benefit from Adjuvant Active Immunotherapy (May 24, 2020). Available at SSRN: https://ssrn.com/abstract=3609259 or http://dx.doi.org/10.2139/ssrn.3609259

Jeany Delafiori

Universidade Estadual de Campinas (UNICAMP) - Innovare Biomarkers Laboratory

Campinas, São Paulo
Brazil

João Carlos Cardoso Alonso

Universidade Estadual de Campinas (UNICAMP)

Cidade Universitária Zeferino Vaz - Barão
Geraldo
Campinas - SP, 13083-970
Brazil

Luiz Augusto dos Santos

Paulínia Municipal Hospital

Paulínia, São Paulo
Brazil

Diogo Noin de Oliveira

Universidade Estadual de Campinas (UNICAMP) - Innovare Biomarkers Laboratory

Campinas, São Paulo
Brazil

Luiz Cláudio Navarro

Universidade Estadual de Campinas (UNICAMP)

Cidade Universitária Zeferino Vaz - Barão
Geraldo
Campinas - SP, 13083-970
Brazil

Estela Natacha Brandt Busanello

Universidade Estadual de Campinas (UNICAMP) - Innovare Biomarkers Laboratory

Campinas, São Paulo
Brazil

Geovana Manzan Sales

Universidade Estadual de Campinas (UNICAMP) - Innovare Biomarkers Laboratory

Campinas, São Paulo
Brazil

Arthur Noin de Oliveira

Universidade Estadual de Campinas (UNICAMP) - Innovare Biomarkers Laboratory

Campinas, São Paulo
Brazil

Anderson Rezende Rocha

Universidade Estadual de Campinas (UNICAMP)

Cidade Universitária Zeferino Vaz - Barão
Geraldo
Campinas - SP, 13083-970
Brazil

Nelson Durán

Universidade Estadual de Campinas (UNICAMP) - Instituto de Quimica

C.P. 6154
13083-970
Brazil

Rodrigo Ramos Catharino

Universidade Estadual de Campinas (UNICAMP) - Innovare Biomarkers Laboratory ( email )

Campinas, São Paulo
Brazil

Wagner Favaro (Contact Author)

Universidade Estadual de Campinas (UNICAMP) ( email )

Cidade Universitária Zeferino Vaz
Departamento de Anatomia, Bloco A,
Campinas - SP, 13083-970
Brazil
55 19 35216104 (Phone)

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