Stevens-Johnson Syndrome: A Perplexing Diagnosis

Cureus Journal of Medical Science, 12(3): e7374. DOI 10.7759/cureus.7374, 2020

10 Pages Posted: 17 Jul 2020

See all articles by Jonathan Dutt

Jonathan Dutt

Southern Illinois University - Family and Community Medicine

Amit Sapra

Southern Illinois University

Pooja Sheth-Dutt

Southern Illinois University - Family and Community Medicine

Priyanka Bhandari

Southern Illinois University

Supriya Gupta

Southern Illinois University - Family and Community Medicine

Date Written: July 7, 2020

Abstract

Stevens-Johnson syndrome/toxic epidermal necrolysis is a spectrum of mucocutaneous reactions that can occur due to drug reactions, infections with Mycoplasma pneumonia, human immunodeficiency virus (HIV), cancer, and genetics. Stevens-Johnson syndrome involves less than 10% of the body surface, while toxic epidermal necrolysis involves greater than 30%. The most common site of the lesions is mucocutaneous surfaces such as the eyes and oral cavity. Our patient was a 44-year-old female who presented to the emergency department with concerns for pain in her eyes, hands and feet, rash, and sore throat. Her rash worsened during the initial hospitalization. This case emphasizes the importance of pattern recognition of Stevens-Johnson syndrome, as this is a rare but serious condition that must be recognized and treated appropriately. The reaction is most commonly due to medications; however, a thorough history and physical exam are vital to diagnosing this potentially fatal condition.

Keywords: stevens-johnson syndrome, toxic epidermal necrolysis, skin rash, drug reaction, sepsis, drug rash, fever, skin biopsy, conjunctivitis

Suggested Citation

Dutt, Jonathan and Sapra, Amit and Sheth-Dutt, Pooja and Bhandari, Priyanka and Gupta, Supriya, Stevens-Johnson Syndrome: A Perplexing Diagnosis (July 7, 2020). Cureus Journal of Medical Science, 12(3): e7374. DOI 10.7759/cureus.7374, 2020, Available at SSRN: https://ssrn.com/abstract=3644755

Jonathan Dutt

Southern Illinois University - Family and Community Medicine ( email )

United States

Amit Sapra (Contact Author)

Southern Illinois University ( email )

Springfield, IL 62703
United States

Pooja Sheth-Dutt

Southern Illinois University - Family and Community Medicine

United States

Priyanka Bhandari

Southern Illinois University

Springfield, IL 62703
United States

Supriya Gupta

Southern Illinois University - Family and Community Medicine

United States

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