Epidemiology, Clinical Characteristics, and Treatment of SARS-CoV-2 Infection in Children: A Narrative Review

40 Pages Posted: 10 Aug 2020

See all articles by Foster Kofi Ayittey

Foster Kofi Ayittey

Curtin University, Malaysia Campus.

Nyasha Bennita Chiwero

Curtin University

Bablu Kumar Dhar

Daffodil International University; Yantai University; Universiti Sains Islam Malaysia (USIM)

Ebenezer Larteh Tettey

37 Military Hospital

Date Written: July 29, 2020


SARS-CoV-2 has infected millions of people around the world, with most cases recorded among adults. The cases reported among children have been acknowledged to be minimal in comparison to adults. Nevertheless, COVID-19 has been reported to affect children at all ages, including newborns. The symptoms among children have also been identified to be similar to those observed among adults, although pediatric patients have been noted to display a spectrum of clinical features ranging from asymptomatic to moderate symptoms. Despite ample publications on the ongoing pandemic, the literature is only replete with guidelines on treating SARS-CoV-2 infection among older people. In this narrative review, comprehensive updates on the infection in children have been discussed. The latest information on the spread of the disease among children around the world, the clinical features observed among the pediatric population, as well as recommended pharmaceutical treatments of COVID-19 among this special group of patients have been covered. Further, expert consensus statements regarding the management of this highly contagious disease among pregnant women and neonates have been discussed. It is believed that this comprehensive review will provide updated information on the epidemiology and clinical features of the ongoing pandemic among pediatric patients. Additionally, the guidelines for handling SARS-CoV-2 among pregnant women and children, as reviewed in this article, are anticipated to be useful to frontline clinicians battling this fatal disease around the globe.

Note: Funding: None to declare

Declaration of Interest: None to declare

Keywords: SARS-CoV-2; COVID-19; Children; Pediatrics; Clinical Features; Epidemiological Characteristics

Suggested Citation

Ayittey, Foster Kofi and Chiwero, Nyasha Bennita and Dhar, Bablu Kumar and Tettey, Ebenezer Larteh, Epidemiology, Clinical Characteristics, and Treatment of SARS-CoV-2 Infection in Children: A Narrative Review (July 29, 2020). Available at SSRN: https://ssrn.com/abstract=3662844 or http://dx.doi.org/10.2139/ssrn.3662844

Foster Kofi Ayittey (Contact Author)

Curtin University, Malaysia Campus. ( email )

CDT 250
Miri, Sarawak 98009

Nyasha Bennita Chiwero

Curtin University

Kent Street
Perth, WA WA 6102

Bablu Kumar Dhar

Daffodil International University ( email )

102 Shukrabad, Mirpur Road
Dhanmondi, Dhaka-1207

Yantai University ( email )

Universiti Sains Islam Malaysia (USIM) ( email )

Bandar Baru Nilai
Nilai, Negeri Sembilan 71800

HOME PAGE: http://https://www.researchgate.net/profile/Bablu_Dhar2/contributions?ev=prf_act

Ebenezer Larteh Tettey

37 Military Hospital


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