Advancing Ethical Stem Cell Research with CRISPR

Stem Cell Therapeutics Ethics section; Current Stem Cell Reports 4, no. 3 (2018): 248-252.

6 Pages Posted: 29 Sep 2020 Last revised: 22 Dec 2021

See all articles by Carolyn Neuhaus

Carolyn Neuhaus

The Hastings Center

Rachel Zacharias

University of Pennsylvania Law School

Date Written: August 1, 2018

Abstract

Purpose of Review The purpose of this review is to highlight opportunities to incorporate Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) into stem cell research in ways that may alleviate long-standing ethical conflicts in biomedical research. Recent Findings CRISPR has been incorporated into stem cell research that aims to understand developmental biology, model disease, test drugs, and develop therapies. In all of these domains, using CRISPR may alleviate, exacerbate, or create ethical conflicts. This review highlights ways in which CRISPR may facilitate more ethical research. Summary Genetically editing stem cells using CRISPR may lead to more ethical research by reducing reliance on animals used in disease modeling and drug screening research and reducing uncertainty ahead of first-in-human uses of stem cell therapies.

Suggested Citation

Neuhaus, Carolyn and Zacharias, Rachel, Advancing Ethical Stem Cell Research with CRISPR (August 1, 2018). Stem Cell Therapeutics Ethics section; Current Stem Cell Reports 4, no. 3 (2018): 248-252. , Available at SSRN: https://ssrn.com/abstract=3672689 or http://dx.doi.org/10.2139/ssrn.3672689

Carolyn Neuhaus

The Hastings Center ( email )

Garrison, NY 10524
United States

Rachel Zacharias (Contact Author)

University of Pennsylvania Law School ( email )

3501 Sansom St
Philadelphia, PA 19104
United States

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