lancet-header

Preprints with The Lancet is a collaboration between The Lancet Group of journals and SSRN to facilitate the open sharing of preprints for early engagement, community comment, and collaboration. Preprints available here are not Lancet publications or necessarily under review with a Lancet journal. These preprints are early-stage research papers that have not been peer-reviewed. The usual SSRN checks and a Lancet-specific check for appropriateness and transparency have been applied. The findings should not be used for clinical or public health decision-making or presented without highlighting these facts. For more information, please see the FAQs.

Primary Care Contact for Mental Illness and Self-Harm Before, During and After the Peak of the COVID-19 Pandemic in the UK: Cohort Study of 13 Million Individuals

25 Pages Posted: 8 Oct 2020

See all articles by Matthew J. Carr

Matthew J. Carr

The University of Manchester - Division of Psychology and Mental Health; The University of Manchester - NIHR Greater Manchester Patient Safety Translational Research Centre (Greater Manchester PSTRC)

Sarah Steeg

The University of Manchester - Manchester Academic Health Science Centre (MAHSC)

Roger T. Webb

The University of Manchester - Division of Psychology and Mental Health; The University of Manchester - NIHR Greater Manchester Patient Safety Translational Research Centre (Greater Manchester PSTRC)

Nav Kapur

The University of Manchester - Division of Psychology and Mental Health; NHS Foundation Trust - Greater Manchester Mental Health and Social Care Trust

Carolyn Chew-Graham

Keele University - School of Medicine

Kathryn Abel

The University of Manchester - Centre for Women’s Mental Health; The University of Manchester - Manchester Academic Health Science Centre (MAHSC)

Holly Hope

The University of Manchester - Centre for Women’s Mental Health

Matthias Pierce

The University of Manchester - Centre for Women’s Mental Health

Darren Ashcroft

The University of Manchester - Manchester Academic Health Science Centre (MAHSC)

More...

Abstract

Background: The Covid-19 pandemic has adversely affected population mental health.

Methods: Using electronic health records from 1714 UK general practices registered with the Clinical Practice Research Datalink we examined incidence and event rates of depression and anxiety disorders, self-harm, prescriptions for antidepressants and benzodiazepines and GP referrals to mental health services per 100,000 person-months, before, during and after the peak of the Covid-19 emergency. Analyses were stratified by gender, age group and practice-level Index of Multiple Deprivation quintile.

Findings: In April 2020, primary care-recorded incident depression reduced by 43·6% (95% CI 39·0% to 47·9%), anxiety disorders by 48·2% (CI 44·6% to 51·5%) and antidepressant prescribing by 36·2% (CI 33·7% to 38·6%) compared to expected rates based on prior trends. Reductions in first diagnoses of depression and anxiety disorders were particularly stark for working-age adults and patients registered at practices in more deprived areas. Self-harm incidence was 38·5% (CI 35·7% to 41·3%) lower than expected in April 2020. Total self-harm contacts fell by 28·2% (CI 25·5% to 30·8%). Rates of both incident and any self-harm remained around thirty percent lower than expected up to June 2020. 

Interpretation: Our findings reveal a stark treatment gap that was greater for first diagnoses of depression and anxiety disorders in working age adults, for practice populations in deprived areas, and for self-harm. Consequences could include more patients subsequently presenting with greater acuity and severity of mental illness and rising rates of non-fatal self-harm and suicide. 

Funding: This work was funded by the National Institute for Health Research (NIHR) Greater Manchester Patient Safety Translational Research Centre, UK Research and Innovation/Medical Research Council COVID-19 Rapid Response Initiative funding and by a University of Manchester Presidential Fellowship (SS). CC-G received funding from the NIHR Applied Research Collaboration West Midlands.

Declaration of Interests: All authors have completed the Unified Competing Interest form (available on request from the corresponding author) and declare: no support from any organisation for the submitted work; no financial relationships with any organisations that might have an interest in the submitted work in the previous three years, no other relationships or activities that could appear to have influenced the submitted work.

Ethics Approval Statement: This study is based on data from the Clinical Practice Research Datalink obtained under license from the UK Medicines and Healthcare products Regulatory Agency. The study was approved by the Independent Scientific Advisory Committee for Clinical Practice Research Datalink research (protocol number 20_094R1).

Keywords: COVID-19, primary health care, mental illness, self-harm, electronic health records, public health.

Suggested Citation

Carr, Matthew J. and Steeg, Sarah and Webb, Roger T. and Kapur, Nav and Chew-Graham, Carolyn and Abel, Kathryn and Hope, Holly and Pierce, Matthias and Ashcroft, Darren, Primary Care Contact for Mental Illness and Self-Harm Before, During and After the Peak of the COVID-19 Pandemic in the UK: Cohort Study of 13 Million Individuals. Available at SSRN: https://ssrn.com/abstract=3706269 or http://dx.doi.org/10.2139/ssrn.3706269

Matthew J. Carr

The University of Manchester - Division of Psychology and Mental Health

United Kingdom

The University of Manchester - NIHR Greater Manchester Patient Safety Translational Research Centre (Greater Manchester PSTRC)

United Kingdom

Sarah Steeg (Contact Author)

The University of Manchester - Manchester Academic Health Science Centre (MAHSC) ( email )

46 Grafton Street
Manchester, M13 9NT
United Kingdom

Roger T. Webb

The University of Manchester - Division of Psychology and Mental Health ( email )

United Kingdom

The University of Manchester - NIHR Greater Manchester Patient Safety Translational Research Centre (Greater Manchester PSTRC) ( email )

United Kingdom

Nav Kapur

The University of Manchester - Division of Psychology and Mental Health

United Kingdom

NHS Foundation Trust - Greater Manchester Mental Health and Social Care Trust

United Kingdom

Carolyn Chew-Graham

Keele University - School of Medicine ( email )

Kathryn Abel

The University of Manchester - Centre for Women’s Mental Health

United Kingdom

The University of Manchester - Manchester Academic Health Science Centre (MAHSC) ( email )

46 Grafton Street
Manchester, M13 9NT
United Kingdom

Holly Hope

The University of Manchester - Centre for Women’s Mental Health ( email )

United Kingdom

Matthias Pierce

The University of Manchester - Centre for Women’s Mental Health

United Kingdom

Darren Ashcroft

The University of Manchester - Manchester Academic Health Science Centre (MAHSC) ( email )

46 Grafton Street
Manchester, M13 9NT
United Kingdom

Click here to go to TheLancet.com

Paper statistics

Downloads
140
Abstract Views
1,814
PlumX Metrics