Halting Coronavirus Replication

Epidemiology Open Journal - International Journal of Epidemiology, 2020; 5(1): 13-15. doi: 10.17140/EPOJ-5-119 (Openventio Publishers)

3 Pages Posted: 5 Nov 2020 Last revised: 16 Feb 2021

Date Written: March 18, 2020

Abstract

Sirtuin 1 (SIRT1) inhibitors can reduce replication of many viruses with certain characteristics similar to those of coronaviruses, while the p53 protein is another important factor in the down-regulation of viral growth. Tenovin is a class of small molecules that inhibit Sirtuin 1 and 2, in addition to activating the p53 protein, by means of regulating the interactions used by coronaviruses as a self-defense mechanism. By blocking virus growth and continuous replication, with already tested antiviral medicines, the promise of coronavirus disease 2019 (COVID-19) eradication exists.

Note: Funding: None.

Declaration of Interests: None.

Keywords: P53, Tumor suppressor,P53, Tenovin-6, COVID-19, SARS-CoV2/COVID-19:, COVID-19 Epidemic, Tenovin-1, coronavirus replication, COVID-19 PANDEMIC, SIRT1 inhibitors

Suggested Citation

Smith, Kira, Halting Coronavirus Replication (March 18, 2020). Epidemiology Open Journal - International Journal of Epidemiology, 2020; 5(1): 13-15. doi: 10.17140/EPOJ-5-119 (Openventio Publishers), Available at SSRN: https://ssrn.com/abstract=

Kira Smith (Contact Author)

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Italy
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