Ethico-Legal and Policy Issues Surrounding Personalised Medicine

In Personalised Health Care: Fostering Precision Medicine Advancements for Gaining Population Health Impact, edited by Stefania Boccia, Róza Ádány, Paolo Villari, Martina Cornel, Corrado De Vito, and Roberta Pastorino, 57–76. SpringerBriefs in Public Health. Springer International Publishing, 2021.

Posted: 10 Mar 2021

See all articles by Roberta Pastorino

Roberta Pastorino

Università Cattolica del Sacro Cuore - Dipartimento di Psicologia

Michael Lang

McGill University - Faculty of Law

Ma'n H. Zawati

McGill University - Centre of Genomics and Policy

Giovanna Elisa Calabrò

affiliation not provided to SSRN

Ilda Hoxhaj

affiliation not provided to SSRN

Elisa J.F. Houwink

affiliation not provided to SSRN

Michele Sassano

affiliation not provided to SSRN

Stefania Boccia

Catholic University of Milan - Dipartimento di Scienze della Salute della donna

Date Written: November 24, 2020

Abstract

The last fifteen years have seen the emergence of Public Health Genomics (PHG), a multidisciplinary field related to the effective and responsible translation of genome-based knowledge and technologies to improve population health. While at the beginning the main concern of PHG was that genetic/genomic applications should be evaluated rigorously before entering into clinical and public health (PH) practice, now the main matter is around the fact that there are some genetic/genomic applications with proved efficacy and cost-effectiveness that should be implemented and become citizens’ rights. In any case, there is a critical need for a robust evaluation process, that takes into account also context-related dimensions (delivery models, economic evaluation and organizational aspects) to facilitate the implementation of these technologies. Systematic reviews of full economic evaluations of genetic/genomic applications are of paramount importance to identify all feasible health programs involving a defined use of a particular genetic/genomic application and to recognize which health programs can maximize the value of that genetic/genomic application. Cost-effectiveness analyses may be useful also in the early stages of the evaluation process to assess which characteristics of a genetic/genomic application need to be improved. Finally, the implementation of genetic/genomics applications requires specific training efforts for public health professional to increase their current level of competence. All these issues are addressed in this chapter, using the population health perspective and the point of view of PH.

Suggested Citation

Pastorino, Roberta and Lang, Michael and Zawati, Ma'n H. and Calabrò, Giovanna Elisa and Hoxhaj, Ilda and Houwink, Elisa J.F. and Sassano, Michele and Boccia, Stefania, Ethico-Legal and Policy Issues Surrounding Personalised Medicine (November 24, 2020). In Personalised Health Care: Fostering Precision Medicine Advancements for Gaining Population Health Impact, edited by Stefania Boccia, Róza Ádány, Paolo Villari, Martina Cornel, Corrado De Vito, and Roberta Pastorino, 57–76. SpringerBriefs in Public Health. Springer International Publishing, 2021. , Available at SSRN: https://ssrn.com/abstract=3766324

Roberta Pastorino

Università Cattolica del Sacro Cuore - Dipartimento di Psicologia ( email )

1 Largo A. Gemelli
Milano (Milan), MI Milano 20123
Italy

Michael Lang

McGill University - Faculty of Law ( email )

3644 Peel Street
Montreal H3A 1W9, Quebec
Canada

Ma'n H. Zawati (Contact Author)

McGill University - Centre of Genomics and Policy ( email )

740 Dr. Penfield Avenue, Suite 5200
Montreal, Quebec H3A 0G1
Canada

Giovanna Elisa Calabrò

affiliation not provided to SSRN

Ilda Hoxhaj

affiliation not provided to SSRN

Elisa J.F. Houwink

affiliation not provided to SSRN

Michele Sassano

affiliation not provided to SSRN

Stefania Boccia

Catholic University of Milan - Dipartimento di Scienze della Salute della donna ( email )

Italy

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